Arterial disorders : definition, clinical manifestations, mechanisms and therapeutic approaches / Adel Berbari, Giuseppe Mancia, editors.

Format:

Book

Contributor:

Berbari, Adel E., editor.

Mancia, Giuseppe, editor.

Language:

English

Subjects (All):

Arteries--Diseases.

Arteries.

Arteries--Diseases--Diagnosis.

Arteries--Diseases--Treatment.

Diagnosis.

Genre:

Electronic books.

Physical Description:

1 online resource (ix, 431 pages) : illustrations

Place of Publication:

Cham : Springer, 2015.

System Details:

Mode of access: World Wide Web.

text file

Summary:

As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental factors. Particular emphasis is placed on recent concepts, such as: the role of age-associated arterial alterations in the initiation and progression of cardiovascular diseases in older persons, the importance of mineral metabolism-bone vascular interactions, the clinical and prognostic significance of the renal resistive index, retinal circulation, toxemia of pregnancy as an arterial disease, and the role of pulmonary/vascular interaction in pulmonary hypertension and cross-talk of macrocirculation and microcirculation in target organ involvement. Evaluation procedures are carefully explained, and the full range of currently available therapeutic options, including lifestyle modifications and pharmacologic approaches, are described and appraised.

Contents:

PART I Introduction: Definition/Epidemiology of arterial disease

PART II Normal structure and physiology of the arterial system

PART III Classification of arterial pathology and clinical manifestations: Atherosclerosis

Arteriosclerosis

Disease of Precapillary resistance vessels

PART IV Pathogenetic mechanisms in arterial disease: Hemodynamic and mechanical factors

Metabolic factors

Inflammatory markers

Neurohormonal interactions

Mineral-bone/ arterial interactions

Endothelial function and impairment

Miscellaneous: Pharmacologic/factors/environmental factors

PART V Systemic arterial disorders: Arterial aging

Diabetes mellitus

Metabolic Syndrome/obesity

Chronic kidney disease/Renovascular interactions

Pulmonary Hypertension/Pulmonary vascular interactions

Systemic vasculitides

Genetic/ degenerative disorders

Hypertension

Toxemia of pregnancy

Kidney transplants, both donors and recipients

PART VI Evaluation procedures: Arterial function

Renal resistive index

Retinal microcirculation

PART VII Therapeutic options: Lifestyle modifications

Pharmacologic approaches.

Notes:

Online resource; title from PDF title page (SpringerLink, viewed March 24, 2015).

ISBN:

9783319145563

3319145568

331914555X

9783319145556

OCLC:

905490643

Access Restriction:

Restricted for use by site license.