Autonomic innervation of the heart : role of molecular imaging / Riemer H.J.A. Slart, René A. Tio, Philip H. Elsinga, Markus Schwaiger, editors.

Format:

Book

Contributor:

Slart, Riemer H. J. A., editor.

Tio, René Anton, 1962- editor.

Elsinga, Philip H., editor.

Schwaiger, Markus, editor.

Language:

English

Subjects (All):

Heart--Innervation--Imaging.

Heart.

Molecular diagnosis.

Heart--Innervation.

Genre:

Electronic books.

Physical Description:

1 online resource (xvii, 465 pages) : illustrations

Place of Publication:

Heidelberg : Springer, 2015.

System Details:

Mode of access: World Wide Web.

text file

Summary:

This book explains in detail the potential value of the hybrid modalities, SPECT-CT and PET-CT, in the imaging of cardiac innervation in a wide range of conditions and diseases, including ischemic heart disease, diabetes mellitus, heart failure, amyloidosis, heart transplantation, and ventricular arrhythmias. Imaging of the brain-heart axis in neurodegenerative disease and stress and of cardiotoxicity is also discussed. The roles of the various available tracers are fully considered, and individual chapters address radiopharmaceutical development under GMP, imaging physics, and kinetic modeling software. Highly relevant background information is included on the autonomic nervous system of the heart and its pathophysiology, and in addition future perspectives are discussed. Awareness of the importance of autonomic innervation of the heart for the optimal management of cardiac patients is growing, and there is an evident need for objective measurement techniques or imaging modalities. In this context, Autonomic Innervation of the Heart will be of wide interest to clinicians, researchers, and industry.

Contents:

Introduction

Autonomic nervous system of the heart

Pathophysiology of the autonomic nervous system of the heart

Tracers for Presynaptic Cardiac Innervation

Tracers of Adrenergic Receptors

Tracers of the Parasympathetic System

Radiopharmaceuticals production under GMP

Physics of PET-CT and SPECT-CT

Kinetics & software PET

SPECT-CT imaging of autonomic innervation in heart diseases

PET-CT imaging of autonomic innervation in heart diseases

Imaging ischemic heart disease

Imaging diabetes mellitus

Imaging heart failure

Imaging amyloidosis

Imaging heart transplantation

Imaging ventricular arrhythmias

Guided therapy & imaging

Imaging the functional brain-heart axis: neurodegenerative diseases

Imaging the functional brain-heart axis: mental stress & anxiety

Imaging cardiotoxicity: the effects of chemo- and mono-clonal antibody therapy on autonomic innervation

Imaging cardiotoxicity: the effect of radiotherapy on autonomic innervation

Summary and Future Perspectives: PET-MRI Imaging of cardiac Innervation, fluorescence imaging of cardiac innervation

Epilog

Index.

Notes:

Includes index.

Online resource; title from PDF title page (SpringerLink, viewed February 5, 2015).

Includes bibliographical references at the end of each chapters and index.

ISBN:

9783662450741

3662450747

3662450739

9783662450734

OCLC:

902675744

Access Restriction:

Restricted for use by site license.