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Pre-Analytics of Pathological Specimens in Oncology / Manfred Dietel, Christian Wittekind, Gianni Bussolati, Moritz von Winterfeld, editors.
- Format:
- Book
- Series:
- Recent results in cancer research ; volume 199.
- Recent results in cancer research
- Language:
- English
- Subjects (All):
- Cancer--Diagnosis.
- Cancer.
- Diagnostic specimens--Analysis.
- Diagnostic specimens.
- Genre:
- Electronic books.
- Physical Description:
- 1 online resource.
- Place of Publication:
- Cham [Switzerland] : Springer, [2015]
- System Details:
- Mode of access: World Wide Web.
- text file
- Summary:
- This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase ? the period from surgical removal of tissue to the start of pathological processing ? have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up.
- Contents:
- What Is Pre-Analytics in Surgical Pathology?
- Histologic Validation of Vacuum Sealed Formalin
- Free Tissue Preservation and Transport System
- Pre-Analytics and Molecular Pathology
- Experiences in Vacuum Preparation of Routine Specimens
- Tissue Heterogeneity as a Pre-Analytical Source of Variability
- Vacuum Fixation of Breast Specimens Before Grossing
- How Do Short Fixation and Rapid Microwave Processing Affect Her2 Testing?
- Current Projects in Pre-Analytics ? Where to Go?
- Nucleic Acid Extraction from FFPE Tissue as Critical Preanalytic Step for NGS Applications
- Experiences With Pre-Analytics of Lung Specimen
- Experiences With Pre-Analytics of GI-Specimen
- Bone Marrow Work-Up
- Two-Temperature Fixation Preserves Activation Status with High Efficiency
- Towards the Lean Lab. The Industry Challenge. .
- Notes:
- Vendor-supplied metadata.
- Includes bibliographical references.
- ISBN:
- 9783319139579
- 3319139576
- 3319139568
- 9783319139562
- OCLC:
- 902675369
- Access Restriction:
- Restricted for use by site license.
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