Neurovascular events after subarachnoid hemorrhage : towards experimental and clinical standardisation / Javier Fandino, Serge Marbacher, Ali-Reza Fathi, Carl Muroi, Emanuela Keller, editors.

Format:

Book

Conference/Event

Contributor:

Fandino, Javier, editor.

Marbacher, Serge, editor.

Fathi, Ali-Reza, editor.

Muroi, Carl, editor.

Keller, Emanuela, editor.

Conference Name:

International Conference on Neurovascular Events after Subarachnoid Hemorrhage (12th : 2013 : Lucerne, Switzerland)

Series:

Acta neurochirurgica. Supplement ; 20.

Acta Neurochirurgica Supplement, 0065-1419 ; 20

Language:

English

Subjects (All):

Subarachnoid hemorrhage--Congresses.

Subarachnoid hemorrhage.

Genre:

Electronic books.

Conference papers and proceedings.

Physical Description:

1 online resource (xiv, 373 pages) : illustrations.

Place of Publication:

Cham : Springer, 2015.

System Details:

Mode of access: World Wide Web.

text file

Summary:

This book contains articles presented at the 12th International Conference on Cerebral Vasospasm, held in Lucerne, Switzerland, in July 2013. The included papers represent a balanced cross-section of the enormous progress achieved in basic and clinical research on aneurysmal subarachnoid hemorrhage and its sequelae, including early neurovascular events and delayed cerebral vasospasm. The section on basic research covers a broad range of aspects, with a special focus on animal models for the study of acute events after experimental subarachnoid hemorrhage. The section on clinical topics encompa.

Contents:

Preface; Acknowledgment; Contents; Vasospasm: My First 25 Years-What Worked? What Didn't? What Next?; History; What Worked: Etiology and Pathogenesis; What Worked: Diagnosis; What Worked: Treatment; Some Noteable Failures; What Next?; Summary; Conclusion; References; : Aneurysm Formation; Molecular Basis for Intracranial Aneurysm Formation; Findings from Studies Performed with Human Intracranial Aneurysms; Molecular Mechanisms Regulating IA Formation Through Linking Hemodynamic Stress and Long-Lasting Inflammation; Future Prospects for the Development of Therapeutic Drugs for IA

ConclusionReferences; Aneurysm Wall Thickness Measurements of Experimental Aneurysms: In Vivo High-Field MR Imaging Versus Direct Microscopy; Introduction; Materials and Methods; Results; Discussion; Clinical Background; Aneurysm Wall Thickness Measurements; Limitations; Conclusions; References; : Early Brain Injury and Neuroprotection; Early Events After Aneurysmal Subarachnoid Hemorrhage; Introduction; Subarachnoid Blood; Mechanical Trauma; Chemical Trauma; Oxyhemoglobin; Heme Metabolism Products; Iron; Bilirubin Oxidation Products (BOXes); Acute Reactive Hyperemia

Cushing Response (CR)Cardiac Complications; Pulmonary Complications; Transient Global Ischemia (TGI); Energy Failure; Ionic Changes; Biochemical and Molecular Mechanisms; Extracellular Glutamate; Nitric Oxide (NO); Endothelin (ET)-1; Inflammation; Oxidative Stress; Conclusion; References; Mouse Genetic Background Is Associated with Variation in Secondary Complications After Subarachnoid Hemorrhage; Introduction; Methods; Animals and SAH Model; Hematoxylin and Eosin Staining; Fluoro-Jade B Staining; Data Quantification and Statistical Analysis; Results; Mortality; MCA Vasospasm

Neuronal Degeneration Discussion; Conclusion; References; The Value of Perfusion Computed Tomography (PCT) Imaging After Aneurysmal Subarachnoid Hemorrhage: A Review of the Current Data; Introduction; Methods; Results; Summary of Early PCT Data; Summary of Subsequent PCT Data; Conclusion; References; Neurovascular Events After Subarachnoid Hemorrhage: Focusing on Subcellular Organelles; Introduction; The Functional Alteration of Organelles Within the Progression of SAH; Nucleus: Transcription Factor Activation

The Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2)-Antioxidant Response Element (ARE) SignalingNF-κB Signaling; Hypoxia-Inducible Factor (HIF)-1; Mitochondrial Dysfunction; Autophagy-Lysosomal System; ER Stress; Future Directions and Conclusion; References; Effects of Diltiazem on Sympathetic Activity in Patients with Aneurysmal Subarachnoid Hemorrhage; Introduction; Patients and Methods; Results; Discussion; Conclusion; References; Haemoglobin Scavenging After Subarachnoid Haemorrhage; Introduction; Materials and Methods; Results; Discussion; Conclusion; References

Notes:

Online resource; title from PDF title page (SpringerLink, viewed December 15, 2014).

Includes indexes.

ISBN:

9783319049816

331904981X

OCLC:

894554074

Access Restriction:

Restricted for use by site license.