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Protein kinase inhibitors in research and medicine / edited by Kevan M. Shokat.

Holman Biotech Commons - Periodicals QP601 .M49 v.1 (1955)-v.148 (1987), v.150 (1987)-v.224 (1993), v.226 (1993)-v.228 (1993), v.230 (1994)-v.242 (1994), v.244 (1994)-v.253 (1995), v.257 (1996)-v.262 (1995), v.266 (1996)-v.284 (1997), v.286 (1997)-v.305 (1999), v.332 (2001)-v.333 (2001), v.341 (2001)-v.342 (2001) v.120 1986 (cum. index to v.81-94, 96-101) v.140 1988 (cum. index to v.102-119, 121-134) v.175 1990 (cum. index to v.135-139, 141-167) v.199 1993 (cum. index to v.168-174, 176-194) v.229 1995 (cum. index to v.195-198, 200-227) v.265 1996 (cum. index to v.228, 230-262) v.285 1998 (cum. index to v.263, 264, 266-289)
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LIBRA QP601 .M49 v.1-v.217, v.219-v.220, v.222-v.288, v.291, v.299, v.303 v.306 (2000)-v.321 (2000) v.323 (2000)-v.331 (2001), v.334 (2001)-v.340 (2001), v.343 (2002)-v.390 (2004) v.320 2000 (cum. index to v.290-319) v.355 2002 (cum. index to v.321-354)
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Format:
Book
Contributor:
Shokat, Kevan, editor.
Series:
Methods in enzymology ; 0076-6879 v. 548.
Methods in enzymology, 0076-6879 ; volume 548
Language:
English
Subjects (All):
Protein kinases--Inhibitors.
Protein kinases.
Protein Kinase Inhibitors.
Medical Subjects:
Protein Kinase Inhibitors.
Physical Description:
xii, 241, 42 unnumbered pages of plates : illustrations (some color) ; 24 cm.
Edition:
First edition.
Place of Publication:
Amsterdam : Elsevier/Academic Press, 2014.
Contents:
Catalytic mechanisms and regulation of protein kinases / Zhihong Wang and Philip A. Cole
A structural atlas of kinases inhibited by clinically approved drugs / Qi Wang, Julie A. Zorn, and John Kuriyan
Fragment-based approaches to the discovery of kinase inhibitors / Paul N. Mortenson, Valerio Berdini, and Marc O'Reilly
Targeting protein kinases with selective and semi-promiscuous covalent inhibitors / Rand M. Miller and Jack Taunton
The resistance tetrad: amino acid hotspots for kinome-wide exploitation of drug-resistant protein kinase alleles / Fiona P. Bailey, Veselin I. Andreev, and Patrick A. Eyers
FLiK: a direct binding assay for the identification and kinetic characterization of stabilizers of inactive kinase conformations / Jeffrey R. Simar and Daniel Rauh
Discovery of allosteric BCR-ABL inhibitors from phenotypic screen to clinical candidate / Nathanael S. Gray and Doriano Fabbro
The logic and design of analog-sensitive kinases and their small molecule inhibitors / Michael S. Lopez, Joseph I. Kliegman, and Kevan M. Shokat.
Notes:
Includes bibliographical references and indexes.
ISBN:
9780123979186
0123979188
OCLC:
894270384
Publisher Number:
9780123979186

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