2 options
Immune biology of allogeneic hematopoietic stem cell transplantation : models in discovery and translation / edited by Gérard Socié and Bruce R. Blazar.
Connect to full text Available online
View onlineElsevier ScienceDirect eBook - Biochemistry, Genetics and Molecular Biology 2013 Available online
View online- Format:
- Book
- Language:
- English
- Subjects (All):
- Hematopoietic stem cells--Transplantation.
- Hematopoietic stem cells.
- Blood--Diseases.
- Blood.
- Immunology.
- Graft versus host disease.
- Hematology.
- Hematopoietic Stem Cell Transplantation.
- Graft vs Host Disease--immunology.
- Transplantation, Homologous--immunology.
- Transplantation Immunology.
- Blood Physiological Phenomena.
- Hematologic Diseases--diagnosis.
- Medical Subjects:
- Hematopoietic Stem Cell Transplantation.
- Graft vs Host Disease--immunology.
- Transplantation, Homologous--immunology.
- Transplantation Immunology.
- Local Subjects:
- Blood Physiological Phenomena.
- Hematologic Diseases--diagnosis.
- Genre:
- Electronic books.
- Physical Description:
- 1 online resource (xviii, 518 pages) : illustrations
- Place of Publication:
- Amsterdam ; Boston : Elsevier/AP, [2013]
- System Details:
- text file
- Summary:
- This book provides clinical and scientific researchers with a deep understanding of the current research and the implications for translational practice. By providing an overview of immune biology of HSCT, an explanation of immune rejection and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia (GVL) effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future.
- Contents:
- Chapter 1
- Overview of the immune biology of allogeneic hematopoietic stem cell transplantation
- Chapter 2
- The HLA system in hematopoietic stem cell transplantation
- Chapter 3
- The impact of minor histocompatibility antigens in allogeneic stem cell transplantation
- Chapter 5
- Immune rejection: the immune biology of allogeneic hematopoietic stem cell transplantation (from mice to humans)
- Chapter 7
- Tumor-associated antigens
- Chapter 8
- Impact of the conditioning regimen
- Chapter 9
- Antigen presentation and antigen-presenting cells in graft-versus-host disease
- Chapter 10
- T-cell costimulation in graft-versus-host disease and graft-versus-leukemia effect
- Chapter 11
- Th1/Th2 and Tc1/Tc2 cells: biology, experimental models and clinical translation
- Chapter 12
- Natural CD4+CD25+FOXP3+ regulatory T cells in graft-versus-host disease
- Chapter 13
- Role of Th17 cells and interleukin 17 in graft-versus-host disease and graft-versus-leukemia reactivity
- Chapter 14
- B and T cells in chronic graft-versus-host disease and graft-versus-leukemia
- Chapter 15
- Natural killer cells in graft-versus-host disease and graft-versus-leukemia
- Chapter 16
- Cytokines in graft-versus-host disease and graft-versus-leukemia
- Chapter 17
- Chemokines and graft-versus-host disease
- Chapter 18
- Intracellular sensors of immunity and allogeneic hematopoietic stem cell transplantation
- Statistical considerations
- Chapter 20
- The endothelium in graft-versus-host disease and graft-versus-leukemia
- Chapter 21
- Looking toward the future: an individualized approach to allogeneic transplantation.
- Notes:
- Includes bibliographical references and index.
- Print version record.
- Other Format:
- Print version: Immune biology of allogeneic hematopoietic stem cell transplantation.
- ISBN:
- 9780123914651
- 0123914655
- OCLC:
- 819635624
- Access Restriction:
- Restricted for use by site license.
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.