Regulated cell death Part B : necroptotic, autophagic and other non-apoptotic mechanisms / edited by Avi Ashkenazi, James A. Wells, Junying Yuan.

Format:

Book

Contributor:

Ashkenazi, Avi.

Yuan, Junying.

Wells, James A.

Series:

Methods in enzymology ; v. 545.

Methods in enzymology, 0076-6879 ; v. 545

Language:

English

Subjects (All):

Cell death.

Autophagic vacuoles.

Physical Description:

xiii, 337 pages, 26 unnumbered pages of plates : illustrations (some color) ; 24 cm.

Edition:

First edition.

Place of Publication:

Amsterdam, Netherlands : Elsevier Academic Press, 2014.

Contents:

Assays for necroptosis and activity of RIP kinases

IAP family of cell death and signaling regulators

Activation of the NLRP3 inflammasome by proteins that signal for necroptosis

Characterization of the ripoptosome and its components: implications for anti-inflammatory and cancer therapy

Tools and techniques to study ligand-receptor interactions and receptor activation by TNF superfamily members

Necrotic cell death in Caenorhabditis elegans

Noncanonical cell death in the nematode Caenorhabditis elegans

Autophagy and cell death in the fly

Structural studies of death receptors

Use of E2~ubiquitin conjugates for the characterization of ubitquitin transfer by RING E3 ligases such as the inhibitor of apoptosis proteins

Muiltidimensional profiling in the invetigation of small-molecule-induced cell death.

Notes:

Includes bibliographical references and indexes.

ISBN:

9780128014301

012801430X

OCLC:

885277085