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Tumor Microenvironment and Cellular Stress : Signaling, Metabolism, Imaging, and Therapeutic Targets / edited by Constantinos Koumenis, Ester Hammond, Amato Giaccia.

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Format:
Book
Author/Creator:
Koumenis, Constantinos, editor.
Contributor:
Hammond, Ester, editor.
Giaccia, Amato, editor.
SpringerLink (Online service)
Series:
Advances in experimental medicine and biology 0065-2598 ; 772.
Advances in experimental medicine and biology
Language:
English
Subjects (All):
Medicine.
Oncology.
Human physiology.
Immunology.
Microbiology.
Physical Description:
1 online resource : illustration.
Contained In:
Springer eBooks
Place of Publication:
New York, NY : Springer New York : Imprint: Springer, 2014.
System Details:
Mode of access: World Wide Web.
text file PDF
Summary:
The collection of chapters in this proceeding volume reflects the latest research presented at the Aegean meeting on Tumor Microenvironment and Cellular Stress held in Crete in Fall of 2012. The book provides critical insight to how the tumor microenvironment affects tumor metabolism, cell stemness, cell viability, genomic instability and more. Additional topics include identifying common pathways that are potential candidates for therapeutic intervention, which will stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery.
Contents:
Introduction
Hypoxia and metabolism in cancer
Hypoxia and Regulation of Cancer Cell Stemness
Hypoxia-mediated metastasis
Escape Mechanisms from Antiangiogenic Therapy: An Immune Cell's Perspective
Hypoxic VDAC1: a potential mitochondrial marker for cancer therapy
Hypoxia directed drug strategies to target the tumor microenvironment
Radiotherapy and the Tumor Microenvironment: Mutual Influence and Clinical Implications
Autophagy and cell death to target cancer cells: exploiting synthetic lethality as cancer therapeutic
Intratumoral Hypoxia as the Genesis of Genetic Instability and Clinical Prognosis in Prostate Cancer
miR-210: Fine-Tuning the Hypoxic Response
The role of complement in tumor growth
Imaging angiogenesis, inflammation and metastasis in the tumor microenvironment with magnetic resonance imaging
Index.
Other Format:
Printed edition:
ISBN:
9781461459156
Access Restriction:
Restricted for use by site license.

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