1 option
The AH receptor in biology and toxicology / edited by Raimo Pohjanvirta.
Holman Biotech Commons RA1242.P73 A35 2012
Available
- Format:
- Book
- Language:
- English
- Subjects (All):
- Polycyclic aromatic hydrocarbons--Toxicology.
- Polycyclic aromatic hydrocarbons.
- Polycyclic aromatic hydrocarbons--Metabolism.
- Dioxins--Toxicology.
- Dioxins.
- Dioxins--Metabolism.
- Nuclear receptors (Biochemistry).
- Transcription factors.
- Dioxins--toxicity.
- Receptors, Aryl Hydrocarbon--agonists.
- Environmental Pollutants--toxicity.
- Receptors, Aryl Hydrocarbon--physiology.
- Risk Assessment.
- Signal Transduction.
- Metabolism.
- Medical Subjects:
- Dioxins--toxicity.
- Receptors, Aryl Hydrocarbon--agonists.
- Environmental Pollutants--toxicity.
- Receptors, Aryl Hydrocarbon--physiology.
- Risk Assessment.
- Signal Transduction.
- Physical Description:
- xiii, 533 pages : illustrations (some color) ; 29 cm
- Place of Publication:
- Hoboken, N.J. : Wiley, [2012]
- Summary:
- In the first book to focus on the topic for toxicologists, chemists, biologists, pharmacologists, and others studying biochemistry, physiology, toxicology, and related disciplines, Pohjanvirta (toxicology, U. of Helsinki, Finland) brings together 35 chapters that review a wide range of aspects of the aryl hydrocarbon receptor (AHR) and its role as a toxicant and a factor in biological processes. Focusing on recent findings, biologists and toxicologists from North America, Europe, and Japan describe the history of research on the protein and its role as a ligand-activated transcription factor, as a mediator of xenobiotic toxicities, and as a physiological regulator. They address dioxin response elements and regulation of gene transcription, functional interactions with other receptors, epigenetic mechanisms, toxicity in laboratory animals, immune regulation, effects of dioxins on teeth and bone, adverse health outcomes in humans, toxicological risk assessment, AHR-active compounds in the human diet, structural and functional diversification of AHRs during metazoan evolution, the role of AHR in various body systems and in control of cell cycle and apoptosis, the circadian clock, and other topics. Annotation ©2012 Book News, Inc., Portland, OR (booknews.com)
- Notes:
- Includes bibliographical references and index.
- ISBN:
- 9780470601822
- 0470601825
- OCLC:
- 723035149
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.