Dendrimer-based drug delivery systems : from theory to practice / edited by Yiyun Cheng.

Format:

Book

Contributor:

Cheng, Yiyun.

Series:

Wiley series in drug discovery and development

Language:

English

Subjects (All):

Dendrimers in medicine.

Drug delivery systems.

Dendrimers--chemistry.

Drug Delivery Systems.

Nanotechnology.

Medical Subjects:

Dendrimers--chemistry.

Drug Delivery Systems.

Nanotechnology.

Physical Description:

xvii, 514 pages : illustrations ; 24 cm.

Place of Publication:

Hoboken, NJ : John Wiley & Sons, [2012]

Summary:

Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs.

With contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug delivery systems. The book analyzes key issues, demonstrating the critical connections that link fundamental concepts, design, synthesis, analytical methodology, and biological assessment to the practical use of dendrimers in drug delivery applications. Topics covered include:

Dendrimer history

Synthesis

Physicochemical properties

Principles of drug delivery

Applications in diverse biomedical fields

Dendrimer-Based Drug Delivery Systems reflects the authors' thorough review and analysis of the current literature as well as their own firsthand experience in the lab. Readers will not only discover the current state of the science, but also gain valuable insights into fruitful directions for future research. References at the end of each chapter serve as a gateway to the growing body of literature in the field, enabling readers to explore each individual topic in greater depth.

Pharmaceutical and biomedical researchers will find this book a unique and essential guide to the opportunities, issues, and challenges involved in fully exploiting the potential of dendrimers to improve drug delivery. Book jacket.

Contents:

Dendrimer chemistry : supramolecular perspectives and applications / Charles N. Moorefield, Sujith Perera, and George R. Newkome

Physicochemical properties of dendrimers and dendrimer complexes / Toyoko Imae

The use of dendrimers to optimize the physicochemical and therapeutic properties of drugs / Nicole Stieger ... [et al.]

Biological properties of phosphorus dendrimers / Anne-Marie Caminade and Jean-Pierre Majoral

Dendrimer-based prodrugs : synthesis and biological evaluation / Mohammad Najlah, Zhengyuan Zhou, and Antony D'Emanuele

Improving the biocompatibility of dendrimers in drug delivery / Yiwen Li, Libo Zhao, and Yiyun Cheng

Degradable dendrimers for drug delivery / Marc Gingras and Myriam Roy

Design of stimuli-responsive dendrimers for biomedical purposes / Chie Kojima

Dendrimer-based gene delivery systems : administration routes and in vivo evaluation / Santander-Orgega M.J., Uchegbu I.F., and Schatzlein A.G.

Triazine dendrimers for DNA and siRNA delivery : progress, challenges, and opportunities / Meredith A Mintzer ... [et al.]

Dendrimer-coated carbohydrate residues as drug delivery : Trojan horses in glycoscience / Yoann M. Chabre and Rene Roy

Nuclear magnetic resonance techniques in the analysis of pamam dendrimer-based drug delivery systems / Xueyan Feng ... [et al.]

Dendrimer-based medical nanodevices for magnetic resonance imaging applications / Hongdong Cai, Mingwu Shen, and Xiangyang Shi

Dendrimer-related nanoparticle systems for computed tomography imaging / Chen Peng and Xiangyang Shi.

Notes:

Includes bibliographical references and index.

ISBN:

9780470460054

0470460059

OCLC:

757912396