Cancer : the outlaw cell / edited by Richard E. LaFond.

Format:

Book

Contributor:

LaFond, Richard E.

Language:

English

Subjects (All):

Cancer--Research.

Cancer.

Cancer cells.

Physical Description:

xvii, 362 pages : illustrations ; 25 cm

Edition:

Third edition.

Place of Publication:

Oxford ; New York : American Chemical Society/Oxford University Press, 2011.

Summary:

We live in an era in which scientific information grows by the day and is so specialized that no one person can possibly absorb and kept abreast of the literature. Substantial developments in science and medicine, powered by developing technologies such as genetic sequencing, proteomics, and nanobiology, have driven cancer research forward, and a review of where we are now is desper-ately needed.

The third edition of Cancer: The Outlaw Cell is a collection of twenty-five focused chapters by leading researchers at the forefront of cancer-research. Authors present the current state of knowledge in chapters on the role of heredity, cancer and telomeres, tumor resistance, and micro RNAs in the pathogenesis of cancer, among other topics, and map out directions for future research and advancement. Full-color figures appear throughout the book, increasing clarity and accessibility. Book jacket.

Contents:

1 Cancer-An Overview / Henry C. Pitot Pitot, Henry C. 1

2 Cell Growth Control and Cancer / Mikhail V. Blagosklonny Blagosklonny, Mikhail V., Chiang J. Li Li, Chiang J., Arthur B. Pardee Pardee, Arthur B. 14

3 Oncogenes / Steven K. Hanks Hanks, Steven K., Stephen R. Hann Hann, Stephen R. 27

4 Role of Heredity / Alfred G. Knudson Knudson, Alfred G. 53

5 Tumor Suppressor Genes / Amanda Frank Frank, Amanda, Julia Pimkina Pimkina, Julia, Maureen E. Murphy Murphy, Maureen E. 67

6 Cell-Surface, Cytoskeleton and Altered Signaling / Elizabeth J. Luna Luna, Elizabeth J. 77

7 Cancer and Stem Cells / Connie J. Eaves Eaves, Connie J. 91

8 The importance of the micro-environment in cancer induction and progression / Roland Meier Meier, Roland, Derek Radisky Radisky, Derek, Mina Bissell Bissell, Mina 100

9 Cancer and Aging / Judith Campisi Campisi, Judith 113

10 Cancer and Telomeres / Julien P. Duxin Duxin, Julien P., Abhishek Saharia Saharia, Abhishek, Sheila A. Stewart Stewart, Sheila A. 123

11 Loss of Genomic Stability in Cancer / Johanna Eddy Eddy, Johanna, Nancy Maizels Maizels, Nancy 139

12 The Role of Inflammation in Cancer / Jon Mallen-St.Clair Mallen-St.Clair, Jon, Dafna Bar-Sagi Bar-Sagi, Dafna 151

13 AIDS and Cancer / Deirdre O'Mahony O'Mahony, Deirdre, Richard F. Little Little, Richard F., Robert Yarchoan Yarchoan, Robert 165

14 Chemical Carcinogenesis / Miriam C. Poirier Poirier, Miriam C., Elizabeth K. Weisburger Weisburger, Elizabeth K. 179

15 Cancer as a Disease of Orderly Tissue Renewal / Donald E. Ingber Ingber, Donald E. 189

16 The Biology of Cancer Metastasis / Isaiah J. Fidler Fidler, Isaiah J., Margaret L. Kripke Kripke, Margaret L. 198

17 Tumor Resistance / George Klein Klein, George, Peter Demant Demant, Peter 211

18 Acquisition of Drug Resistance / Mehmet Burcu Burcu, Mehmet, Maria R. Baer Baer, Maria R. 225

19 Apoptosis and Cancer / Jessica Plati Plati, Jessica, Walter Malorni Malorni, Walter, Roy a Khosravi-Far Khosravi-Far, Roy a 240

20 Cancer Vaccines / Elizabeth M. Jaffee Jaffee, Elizabeth M., Michel Kafrouni Kafrouni, Michel 255

21 Immunotherapy / Michael Boyiadzis Boyiadzis, Michael, Kenneth Foon Foon, Kenneth, Ronald B. Herberman Herberman, Ronald B. 270

22 Tracing the Trajectory of Cancer Curability / Philip Rubin Rubin, Philip 281

23 Zebrafish Models of Cancer / Alyson MacInnes MacInnes, Alyson, Adam Amsterdam Amsterdam, Adam, Nancy Hopkins Hopkins, Nancy, Jacqueline Lees Lees, Jacqueline 324

24 MicroRNAs in the Pathogenesis of Cancer / Scott M. Hammond Hammond, Scott M. 335.

Notes:

Includes index.

ISBN:

9780841200005

0841200009

9780199767281

0199767289

OCLC:

644150144