Systematic Reviews in Health Care : A Practical Guide / Paul Glasziou, Les Irwig, Chris Bain, Graham Colditz.

Format:

Book

Contributor:

Glasziou, Paul, 1954-

Irwig, Les.

Bain, Chris.

Colditz, Graham.

Series:

Cambridge books online.

Language:

English

Subjects (All):

Systematic reviews (Medical research).

Evidence-based medicine.

Meta-analysis.

Physical Description:

1 online resource (148 pages) : digital, PDF file(s)

Place of Publication:

Cambridge : Cambridge University Press, 2001.

System Details:

Mode of access: World Wide Web.

text file

PDF

Summary:

A practical and clear guide to systematic reviews suitable for all clinical researchers.

Contents:

How much work is a systematic review? 4

1 The question

1.1 What types of questions can be asked? 9

1.2 What is the relevant question? 14

1.3 How focused should the question be? 14

2 Finding relevant studies

2.1 Finding existing systematic reviews 16

2.2 Finding published primary studies 16

2.3 Finding unpublished primary studies 23

2.4 Publication bias

a crucial problem 24

3 Appraising and selecting studies

3.1 Standardizing the appraisal 27

3.2 Using the quality appraisal 29

4 Summarizing and synthesizing the studies

4.1 Presenting the results of the studies (data extraction) 32

4.2 Synthesis of study results 33

4.3 Heterogeneity and effect modification 37

4.4 Detecting publication bias 41

5 Applicability: returning to the question 45

Part 2 Question-specific methods

6 Interventions

6.1 The question 53

6.2 Finding relevant studies 54

6.3 Appraising and selecting studies 55

6.4 Synthesis of study results 57

6.5 Economic evaluation 62

Questions for Part 2: interventions 64

7 Frequency and rate

7.1 The question 67

7.2 Finding relevant studies 68

7.3 Appraising and selecting studies 70

7.4 Summarizing and synthesizing the studies 71

Questions for Part 2: frequency 73

8 Diagnostic tests

8.1 The question 74

8.2 Finding relevant studies 75

8.3 Appraising and selecting studies 78

8.4 Summarizing and synthesizing the studies 83

Questions for Part 2: diagnostic tests 87

9 Aetiology and risk factors

9.1 The question 90

9.2 Finding relevant studies 91

9.3 Appraising and selecting studies 93

9.4 Summarizing and synthesizing the studies 95

9.5 Judging causality 99

Questions for Part 2: aetiology and risk 99

10 Prediction: prognosis and risk

10.1 The question 102

10.2 Finding relevant studies 103

10.3 Appraising and selecting studies 104

10.4 Summarizing and synthesizing the studies 105

Appendix A Literature searching 109

Finding existing systematic reviews 109

Finding randomized trials 111

PubMed clinical queries using research methodology filters 112

Appendix B Software for meta-analysis 114

Meta-analysis of intervention study 114

Meta-analysis of diagnostic tests 116.

Notes:

Title from publishers bibliographic system (viewed on 30 Apr 2012).

Other Format:

Print version:

ISBN:

9780511543500

9780521799621

Access Restriction:

Restricted for use by site license.