Myasthenia gravis and myasthenic disorders / edited by Andrew G. Engel.

Format:

Book

Contributor:

Engel, Andrew.

Gail and Warren Lieberfarb Mental Health and Neuroscience Library Resources Fund.

Series:

Contemporary neurology series ; 0069-9446 81.

Contemporary neurology series ; 81

Language:

English

Subjects (All):

Myasthenia gravis.

Myasthenia Gravis.

Neuromuscular Junction Diseases.

Medical Subjects:

Myasthenia Gravis.

Neuromuscular Junction Diseases.

Physical Description:

xvi, 286 pages : illustrations (some color) ; 26 cm.

Edition:

Second edition.

Place of Publication:

New York : Oxford University Press, [2012]

Summary:

Myasthenia Gravis and Myasthenic Disorders, Second Edition is a thoroughly re-written and updated version of the highly successful first edition published in 1999. The current edition begins with an overview of the anatomy and molecular architecture of the neuromuscular junction and theelectrophysiologic diagnosis of its disorders. The introductory chapters are followed by a detailed exposition of the pathogenesis, natural history, diagnosis and therapy of the autoimmune myasthenias, the Lambert-Eaton myasthenic syndrome, and the increasingly complex and fascinating diseasescollectively referred to as congenital myasthenic syndromes. The acetylcholine receptor is a major target of both autoimmune and inherited myasthenias and a separate chapter reviews its structural and functional properties. The book also describes disorders that often target terminal nerve segmentnear the neuromuscular junction - the syndrome of peripheral nerve hyperexcitability and the Guillain-Barre syndrome. Comprehensively written by leaders at the forefront of research, not to mention thoroughly referenced throughout and gorgeously illustrated, this new edition of the classic 1999 text will cement its place as the text on Myasthenia Gravis and related disorders for years to come.

Contents:

The anatomy and molecular architecture of the neuromuscular junction / Andrew G. Engel

Electrodiagnosis of myasthenic disorders / Michel Harper

The immunopathogenesis of myasthenia gravis / Reinhard Hohlfeld, Hartmut Wekerle, and Alexander Marx

Natural history of myasthenia gravis / Vladimir Luchanok and Henry J. Kaminski

The diagnosis of myasthenia gravis and other disorders of neuromuscular transmission / James F. Howard

Therapy of myasthenia gravis / Daniel B. Drachman

The Lambert-Eaton myasthenic syndrome / Vern C. Juel and Donald B. Sanders

Congenital myasthenic syndromes / Andrew G. Engel ... [et al.]

End-plate acetylcholine receptor : a target for myasthenic disorders : structural and mechanistic essentials / Steven M. Sine and Andrew G. Engel

Peripheral nerve hyperexcitability syndromes / Srikanth Muppidi and Steven Vernino

Effects of antiganglioside antibodies at the neuromuscular junction / Jaap J. Plomp and Hugh J. Willison.

Notes:

Includes bibliographical references and index.

Local Notes:

Acquired for the Penn Libraries with assistance from the Gail and Warren Lieberfarb Mental Health and Neuroscience Library Resources Fund.

ISBN:

9780199738670

019973867X

OCLC:

743275912