Silicon carbide biotechnology : a biocompatible semiconductor for advanced biomedical devices and applications / Stephen E. Saddow.

Format:

Book

Author/Creator:

Saddow, Stephen E.

Language:

English

Subjects (All):

Biomedical materials.

Silicon carbide--Biotechnology.

Silicon carbide.

Biocompatible Materials.

Carbon Compounds, Inorganic.

Semiconductors.

Silicon Compounds.

Biotechnology.

Medical Subjects:

Biocompatible Materials.

Carbon Compounds, Inorganic.

Semiconductors.

Silicon Compounds.

Physical Description:

xvi, 479 pages : illustrations ; 24 cm

Edition:

First edition.

Place of Publication:

Waltham, MA : Elsevier, 2012.

Summary:

One of the major problems facing the biomaterials community today is the lack of biocompatible materials that are also capable of electronic operation. Such devices are currently implemented using silicon, which either has to be hermetically sealed so it cannot interact with the body, or else the material is stable in vivo only for short periods of time. Particularly for permanent or long-term devices such as glucose sensors, brain-machine-interface devices, and smart bone and organ implants, a more robust, biocompatible material that the body does not recognize and reject is urgently needed. Silicon Carbide has proven to be one of the most interesting candidate materials to meet this challenge, with recent research pointing towards long-term biocompatible usage of the material with concurrent advanced operational capabilities, across applications as diverse as heart stent coatings, bone implant scaffolds, neurological implants and in vivo biosensors.

This multi-contributor edited reference work directly addresses the formidable scientific and technological challenges of adapting this well-known material to use in the novel biomedical environment. Providing detailed analysis within topics of current interest, the work synthesizes expertise from the materials and biomedical engineering communities with the goal of supporting future devices. The book is principally for researchers seeking to review the current state of knowledge in the rapidly expanding field, as well as practitioners and technologists looking to implement advanced engineering solutions to present challenges. Book jacket.

Contents:

Silicon carbide materials for biomedical applications

SiC films and coatings : amorphous, polycrystalline, and single crystal forms

Multi-functional SiC surfaces : from passivation to biofunctionalization

SiC in-vitro biocompatibility : epidermal and connective tissue cells

Hemocompatibility assessment of 3C-SiC for cardiovascular applications

Biocompatibility of SiC for neurological applications

SiC for brain-machine interfaces (BMI)

Porous SiC microdialysis technolgy

Biocompatible sol-gel based nanostructured hydroxyapatite coatings on nano-porous SiC

Silicon carbide bioMEMS

SiC as a bio-compatible marker for cell labeling

Carbon based materials on SiC for advanced biomedical applications.

Notes:

Includes bibliographical references and index.

ISBN:

9780123859068

0123859069

OCLC:

743275922