Handbook of statistical bioinformatics / Henry Horng-Shing Lu, Bernhard Schölkopf, Hongyu Zhao, editors.

Format:

Book

Contributor:

Lu, Henry Horng-Shing.

Schölkopf, Bernhard.

Zhao, Hongyu.

Series:

Springer handbooks of computational statistics

Language:

English

Subjects (All):

Computational biology--Handbooks, manuals, etc--Statistical methods.

Computational biology.

Bioinformatics--Handbooks, manuals, etc--Statistical methods.

Bioinformatics.

Statistics.

Genre:

Handbooks and manuals.

Physical Description:

ix, 627 pages : illustrations (some color) ; 24 cm.

Place of Publication:

Heidelberg ; New York : Springer, 2011.

Summary:

Numerous fascinating breakthroughs in biotechnology have generated large volumes and diverse types of high throughput data that demand the development of efficient and appropriate tools in computational statistics integrated with biological knowledge and computational algorithms. This volume collects contributed chapters from leading researchers to survey the many active research topics and promote the visibility of this research area. This volume is intended to provide an introductory and reference book for students and researchers who are interested in the recent developments of computational statistics in computational biology. Book jacket.

Contents:

Part I Sequence Analysis

1 Accuracy Assessment of Consensus Sequence from Shotgun Sequencing / Lei M. Li Li, Lei M. 3

2 Statistical and Computational Studies on Alternative Splicing / Liang Chen Chen, Liang 31

3 Statistical Learning and Modeling of TF-DNA Binding / Bo Jiang Jiang, Bo, Jun S. Liu Liu, Jun S. 55

4 Computational Promoter Prediction in a Vertebrate Genome / Michael Q. Zhang Zhang, Michael Q. 73

5 Discovering Influential Variables: A General Computer Intensive Method for Common Genetic Disorders / Tian Zheng Zheng, Tian, Herman Chernoff Chernoff, Herman, Inchi Hu Hu, Inchi, Iuliana Ionita-Laza Ionita-Laza, Iuliana, Shaw-Hwa Lo Lo, Shaw-Hwa 87

6 STORMSeq: A Method for Ranking Regulatory Sequences by Integrating Experimental Datasets with Diverse Computational Predictions / Jim C. Huang Huang, Jim C., Brendan J. Frey Frey, Brendan J. 109

7 Mixture Tree Construction and Its Applications / Grace S.C. Chen Chen, Grace S.C., Mingze Li Li, Mingze, Michael Rosenberg Rosenberg, Michael, Bruce Lindsay Lindsay, Bruce 135

Part II Expression Data Analysis

8 Experimental Designs and ANOVA for Microarray Data / Richard E. Kennedy Kennedy, Richard E., Xiangqin Cui Cui, Xiangqin 151

9 The Micro Array Quality Control (MAQC) Project and Cross-Platform Analysis of Microarray Data / Zhining Wen Wen, Zhining, Zhenqiang Su Su, Zhenqiang, Jie Liu Liu, Jie, Baitang Ning Ning, Baitang, Lei Guo Guo, Lei, Weida Tong Tong, Weida, Leming Shi Shi, Leming 171

10 A Survey of Classification Techniques for Microarray Data Analysis / Wai-Ki Yip Yip, Wai-Ki, Samir B. Amin Amin, Samir B., Cheng Li Li, Cheng 193

11 Statistical Analysis of Single Nucleotide Polymorphism Microarrays in Cancer Studies / Prterre Neuvial Neuvial, Prterre, Henrik Bengtsson Bengtsson, Henrik, Terence P. Speed Speed, Terence P. 225

12 Computational Analysis of ChIP-chip Data / Hongkai Ji Ji, Hongkai 257

13 eQTL Mapping for Functional Classes of Saccharomyces cerevisiae Genes with Multivariate Sparse Partial Least Squares Regression / Dongjun Chung Chung, Dongjun, Sündüz Keles Keles, Sündüz 283

14 Statistical Analysis of Time Course Microarray Data / Lingyan Ruan Ruan, Lingyan, Ming Yuan Yuan, Ming 299

Part III Systems Biology

15 Kernel Methods in Bioinformatics / Karsten M. Borgwardt Borgwardt, Karsten M. 317

16 Graph Classification Methods in Chemoinformatics / Koji Tsuda Tsuda, Koji 335

17 Hidden Markov Random Field Models for Network-Based Analysis of Genomic Data / Hongzhe Li Li, Hongzhe 353

18 Review of Weighted Gene Coexpression Network Analysis / Tova Fuller Fuller, Tova, Peter Langfelder Langfelder, Peter, Angela Presson Presson, Angela, Steve Horvath Horvath, Steve 369

19 Liquid Association and Related Ideas in Quantifying Changes in Correlation / Ker-Chau Li Li, Ker-Chau 389

20 Boolean Networks / Tung-Hung Chueh Chueh, Tung-Hung, Henry Horng-Shing Lu Lu, Henry Horng-Shing 405

21 Protein Interaction Networks: Protein Domain Interaction and Protein Function Prediction / Yanjun Qi Qi, Yanjun, William Stafford Noble Noble, William Stafford 427

22 Reverse Engineering of Gene Regulation Networks with an Application to the DREAM4 in silico Network Challenge / Hyonho Chun Chun, Hyonho, Jia Kang Kang, Jia, Xianghua Zhang Zhang, Xianghua, Minghua Deng Deng, Minghua, Haisu Ma Ma, Haisu, Hongyu Zhao Zhao, Hongyu 461

23 Inferring Signaling and Gene Regulatory Network from Genetic and Genomic Information / Zhidong Tu Tu, Zhidong, Jun Zhu Zhu, Jun, Fengzhu Sun Sun, Fengzhu 479

24 Computational Drug Target Pathway Discovery: A Bayesian Network Approach / Seiya Imoto Imoto, Seiya, Yoshinori Tamada Tamada, Yoshinori, Hiromitsu Araki Araki, Hiromitsu, Satoru Miyano Miyano, Satoru 501

25 Cancer Systems Biology / Elana J. Fertig Fertig, Elana J., Ludmila V. Danilova Danilova, Ludmila V., Michael F. Ochs Ochs, Michael F. 533

26 Comparative Genomics / Xuhua Xia Xia, Xuhua 567

27 Robust Control of Immune Systems Under Noises: Stochastic Game Approach / Bor-Sen Chen Chen, Bor-Sen, Chia-Hung Chang Chang, Chia-Hung, Yung-Jen Chuang Chuang, Yung-Jen 601.

Notes:

Includes bibliographical references.

ISBN:

9783642163449

3642163440

OCLC:

668190710