The molecular immunology of complex carbohydrates-3 / Albert M. Wu, editor.

Format:

Book

Conference/Event

Contributor:

Wu, Albert M.

Conference Name:

International Symposium on Molecular Immunology of Complex Carbohydrates (3rd : 2007 ; Taipei, Taiwan)

International Symposium on Glycoconjugates (19th : 2007 : Cairns, Australia)

Series:

Advances in experimental medicine and biology ; v. 705.

Advances in experimental medicine and biology

Language:

English

Subjects (All):

Carbohydrates--Immunology--Congresses.

Carbohydrates.

Glycoproteins--Immunology--Congresses.

Glycoproteins.

Glycolipids--Immunology--Congresses.

Glycolipids.

Lectins--Immunology--Congresses.

Lectins.

Glycoconjugates--Immunology--Congresses.

Glycoconjugates.

Carbohydrates--immunology.

Immunology.

Carbohydrates--Immunology.

Medical Subjects:

Carbohydrates--immunology.

Glycoconjugates.

Genre:

Conference papers and proceedings.

Physical Description:

xxxv, 809 pages : illustrations (some color) ; 24 cm.

Place of Publication:

New York : Springer Science+Business Media, [2011]

Summary:

Based on the proceedings of the third international symposium on "Molecular Immunology of Complex Carbohydrates," this text is the latest in a series dedicated to glycotopes, structures and functions of complex carbohydrates, recognition factors of lectins, biomolecular interactions and other glycosciences.

Section I of the book pays tribute to three pioneers in the field-Walter T.J. Morgan, Elvin A. Kabat and especially Winifred M. Watkins; it presents advanced concepts concerning the structure and functions of Blood group ABH/Le-related antigens, offering a comprehensive review on human blood group ABH/Ii, Le^a,b,x,y and siayl Le^a,x glycotopes of human ovarian cyst glycoproteins. Section II covers the interactions of plant, bacterial and animal lectins with carbohydrates and proteins. Section III describes the structures and functions of gangliosides and microbial glycolipids. Section IV covers the physiological roles of other clyeocunjugates in humans, animals, sponges and bacteria as well as aging-related alterations of glycosylation profile in humans. Section V discusses the role of carbohydrates as antigens and regulators of the immune response. Section VI addresses some aspects of the glycobiology of cancer. And section VII details new methodologies in glycol-synthesis and lectin-carbohydrate binding assays and strategies for treatment as crucial applications. Book jacket.

Contents:

pt. 1. Introduction to glyco-experiences. Serendipity in scientific discoveries: some examples in glycosciences / Yuan-Chuan Lee

My 30-year devotion to the N-linked oligosaccharaide structures / Noriko Takahashi

pt. 2. Blood group ABH/Le-related antigens. Human blood group ABH/Ii, Le[a],[b],[x],[y], and Sialyl Le[a],[x] glycotopes: internal structures; and immunochemical roles of human ovarian cyst glycoproteins / Albert M. Wu

Lewis glyco-epitopes: structure, biosynthesis, and functions / Hui-Li Chen

A unique endo-[Beta]-galactosidase that cleaves both blood group A and B glycotopes / Su-Chen Li, Kimberly M. Anderson, and Yu-Teh Li

pt. 3. Lectins. Recognition roles of mammalian structural units and polyvalency in lectin-glycan interactions / Albert M. Wu ... [et al.]

Adhesian/growth-regulatory galectins: insights into their ligand selectivity using natural glycoproteins and glycotopes / Albert M. Wu ... [et al.]

Glycotope structures and intramolecular affinity factors of plant lectins for Tn/T antigens / Pierre Rougé ... [et al.]

The five bacterial lectins (PA-IL, PA-IIL, RSL, RS-IIL, and CV-IIL): interactions with diverse animal cells and glycoproteins / Nechama Gilboa-Garber ... [et al.]

On the differential sialic acid specificity of lectins from different parts of Saraca indica / Bishnu P. Chatterjee and Mainak Majumder

Regulation of lectin production by the human pathogens Pseudomonas aeruginosa and Chromobacterium violaceum: effects of choline, trehalose, and ethanol / Nachman C. Garber ... [et al.]

Non-carbohydrate-mediated interaction of lectins with plant proteins / Jared Q. Gerlach ... [et al.]

Novel concepts about the role of lectins in the plant cell / Els. J.M. Van Damme

pt. 4. Structures and functions of glycolipids. Role of gangliosides and plasma membrane-associated sialidase in the process of cell membrane organization / Sandro Sonnino ... [et al.]

9-O-acetyl GD3 in lymphoid and erythroid cells / Kankana Mukherjee ... [et al.]

GM3 upregulation of matrix metalloproteinase-9 possibly through PI3K, AKT, RICTOR, RHOGDI-2, and TNF-A pathways in mouse melanoma B16 cells / Pu Wang ... [et al.]

Pathological roles of ganglioside mimicry in Guillain-Barré syndrome and related neuropathies / Robert K. Yu ... [et al.]

Structure and function of glycolipids in thermophilic bacteria / Feng-Ling Yang, Yu-Liang Yang, and Shih-Hsiung Wu

Lipooligosaccharides of Neisseria species: similarity between N. polysaccharea and N. meningitidis LOSs / Chao-Ming Tsai

pt. 5. Structures and functions of complex carbohydrates. Roles for N- and O-glycans in early mouse development / Suzannah A. Williams and Pamela Stanley

Glycobiology in the field of gerontology (glycogerontology) / Akira Kobata

Galectins in regulation of apoptosis / Fu-Tong Liu ... [et al.]

Avian and human influenza virus receptors and their distribution / Yasuo Suzuki

Importance of a factor VIIIc-like glycoprotein expressed in capillary endothelial cells (eFactor VIIIc) in angiogenesis / Dipak K. Banerjee ... [et al.]

Mucin O-glycan branching enzymes: structure, function, and gene regulation / Pi-Wan Cheng and Prakash Radhakrishnan

Studying carbohydrate self-recognition in marine sponges using synthetic aggregation factor epitopes / Johannis P. Kamerling and Adriana Carvalho de Souza

Docking of chitin oligomers and nod factors on lectin domains of the LysM-RLK receptors in the Medicago-Rhizobium symbiosis / Pierre Rougé ... [et al.]

pt. 6. Glycoimmunology. O-acetylated sialic acides and their role in immune defense / Roland Schauer ... [et al.]

Sialylated and sulfated carbohydrate ligands for selectins and siglecs: involvement in traffic and homing of human memory T and B lymphocytes / Reiji Kannagi ... [et al.]

Diversity of natural anti-[alpha]-galactosyl antibodies in human serum / Elwira Lisowska and Maria Duk

Significance of serum glycoprotein profiles in spontaneous tolerance after liver allograft transplantation / Pei-Weng Wang and Tai-Long Pan

pt. 7. Glycobiology of cancer. Hematogenous metastasis: roles of CD44v and alternative sialofucosylated selectin ligands / Konstantinos Konstantopoulos and Susan N. Thomas

Regulation of glycosyltransferase genes in apoptotic breast cancer cells induced by L-PPMP and cisplatin / Rui Ma ... [et al.]

Aberrant glycosphingolipid expression and membrane organization in tumor cells: consequences on tumor-host interactions / Alessandro Prinetti ... [et al.]

Human KDN (deaminated neuraminic acid) and its elevated epxression in cancer cells: mechanism and significance / Sadako Inoue ... [et al.]

Polysialic acid bioengineering of cancer and neuronal cells by N-acyl sialic acid precursor treatment / Robert A. Pon, Wei Zou, and Harold J. Jennings

pt. 8. Glyco applications. Synthesis of hemagglutinin-binding trisaccharides / Cheng-Chung Wang ... [et al.]

Fabrication and applications of glyconanomaterials / Po-Chiao Lin, Avijit Kumar Adak, and Chun-Cheng Lin

Glycan arrays to decipher the specificity of plant lectins / Els J.M. Van Damme ... [et al.]

Targeting c-type lectin for the treatment of flavivirus infections / Szu-Ting Chen ... [et al.]

Appendix

Index.

Notes:

"This is the third time I have organized the international symposium on Molecular Immunology of Complex Carbohydrates (MICC), which was held at the Institute of Biological Chemistry (IBC), Academia Sinica, Taipei, Taiwan, 8-12 July 2007, as a satellite meeting of the 19th International Glycoconjugate Organization (IGO) meeting held 15-20 July 2007 in Cairns, Australia"--Pref.

Includes bibliographical references and index.

ISBN:

9781441978769

1441978763

9781441978776

1441978771

OCLC:

690089254