Osteoporosis research : animal models / Gustavo Duque, Ken Watanabe, (editors).

Format:

Book

Contributor:

Duque, Gustavo.

Watanabe, Ken, Ph.D.

Language:

English

Subjects (All):

Animal models.

Osteoporosis--Animal models.

Osteoporosis.

Osteoporosis--Research.

Research.

Physical Description:

xix, 196 pages : illustrations (some color) ; 27 cm

Place of Publication:

London : Springer, 2011.

Summary:

Osteoporosis Research - Animal Models, presents in a very illustrative and practical manner, general methodologies of bone studies in animals, as well as the particular features of the most commonly used animal models in the field.

Research in the field of osteoporosis has grown in recent years. This has resulted in significant advances in determining the causes of osteoporosis, assessing risk factors, and creating new treatment methods. The use of animal models provides important knowledge about pathological conditions that can eventually lead to the development of more effective clinical treatment of diseases in both humans and animals.

Osteoporosis Research - Animal Models, is an essential tool for researchers in the bone field. This book aids researchers in selecting their appropriate model and highlights the experiments that can be strategically designed to optimize the potential of an animal to develop the cardinal features of osteoporosis in humans. This book addresses the importance of recent findings from animal models and their significance on the pathogenesis of osteoporosis in relation to human disease. Book jacket.

Contents:

1 How to Select Your Animal Model for Osteoporosis Research / A. Simon Turner Turner, A. Simon 1

2 Skeletal Phenotyping in Rodents: Tissue Isolation and Manipulation / Janet E. Henderson Henderson, Janet E., Chan Gao Gao, Chan, Edward J. Harvey Harvey, Edward J. 13

3 Methods in Bone Biology in Animals: Biomechanics / José B. Volpon Volpon, José B., Antonio C. Shimano Shimano, Antonio C. 29

4 Methods in Bone Histomorphometry for Animal Models / Natalie Dion Dion, Natalie, Audray Fortin Fortin, Audray, Louis-Georges Ste-Marie Ste-Marie, Louis-Georges 37

5 Methods in Bone Biology in Animals: Imaging / Blaine A. Christiansen Christiansen, Blaine A., Mary L. Bouxsein Bouxsein, Mary L. 45

6 Methods in Bone Biology in Animals: Biochemical Markers / Markus Herrmann Herrmann, Markus 57

7 Methods in Bone Biology: Cancer and Bone / Yu Zheng Zheng, Yu, Markus J. Seibel Seibel, Markus J., Hong Zhou Zhou, Hong 83

8 How to Test Osteoporosis Treatments in Experimental Animals / Robert J. van 't Hof Hof, Robert J. van 't 93

9 The Ovariectomized Mice and Rats / Jameela Banu Banu, Jameela 101

10 Classical Models of Senile Osteoporosis / Ken Watanabe Watanabe, Ken 115

11 Animal Models of Premature Aging / Lee Wei Li Li, Lee Wei, Gustavo Duque Duque, Gustavo 123

12 Nonhuman Primate Models of Osteoporosis / Susan Y. Smith Smith, Susan Y., Aurore Varela Varela, Aurore, Jacquelin Jolette Jolette, Jacquelin 135

13 Other Large Animal Models / Susan Reinwald Reinwald, Susan, David B. Burr Burr, David B. 159

14 Mouse Models for the Study of Fracture Healing and Bone Regeneration / Joerg H. Holstein Holstein, Joerg H., Patric Garcia Garcia, Patric, Tina Histing Histing, Tina, Moritz Klein Klein, Moritz, Stephen Becker Becker, Stephen, Michael D. Menger Menger, Michael D., Tim Pohlemann Pohlemann, Tim 175.

Notes:

Includes bibliographical references and index.

ISBN:

0857292927

9780857292926

OCLC:

706920544