Carbon Nanotubes for Biomedical Applications / Rüdiger Klingeler, Robert B. Sim, editors.

Format:

Book

Contributor:

Klingeler, Rüdiger.

Sim, Robert B.

Language:

English

Subjects (All):

Nanomedicine.

Nanostructures.

Nanostructured materials--Therapeutic use.

Nanostructured materials.

Nanotechnology.

Biomedical materials.

Biomedical engineering.

Physical Description:

xvii, 278 pages : illustrations ; 24 cm

Place of Publication:

Berlin ; New York : Springer, [2011]

Summary:

This book explores the potential of multi-functional carbon nanotubes for biomedical applications. It combines contributions from chemistry, physics, biology, engineering, and medicine. The complete overview of the state-of-the-art addresses different synthesis and biofunctionalisation routes and shows the structural and magnetic properties of nanotubes relevant to biomedical applications. Particular emphasis is put on the interaction of carbon nanotubes with biological environments, i.e. toxicity, biocompatibility, cellular uptake, intracellular distribution, interaction with the immune system and environmental impact. The insertion of NMR-active substances allows diagnostic usage as markers and sensors, e.g. for imaging and contactless local temperature sensing. The potential of nanotubes for therapeutic applications is highlighted by studies on-chemotherapeutic drug filling and release, targeting and magnetic hyperthermia studies for anti-cancer treatment at the cellular level. Book jacket.

Contents:

Part I Fundamentals: Synthesis of Multifunctional Nanomaterials and their Potential for Medical Application

Physical Properties of Carbon Nanotubes for Therapeutic Applications / Vittoria Raffa Raffa, Vittoria, Orazio Vittorio Vittorio, Orazio, Cristina Riggio Riggio, Cristina, Gianni Ciofani Ciofani, Gianni, Alfred Cuschieri Cuschieri, Alfred 3

Carbon Nanotubes in Regenerative Medicine / Bhavna S. Paratala Paratala, Bhavna S., Balaji Sitharaman Sitharaman, Balaji 27

Filling of Carbon Nanotubes with Compounds in Solution or Melted Phase / P. Lukanov Lukanov, P., C.-M. Tilmaciu Tilmaciu, C.-M., A. M. Galibert Galibert, A. M., B. Soula Soula, B., E. Flahaut Flahaut, E. 41

Filling of Carbon Nanotubes: Containers for Magnetic Probes and Drug Delivery / E. Borowiak-Palen Borowiak-Palen, E., C. Tripisciano Tripisciano, C., M. Rümmeli Rümmeli, M., S. Costa Costa, S., X. Chen Chen, X., R. J. Kalenczuk Kalenczuk, R. J. 67

Part II Magnetically Functionalised Carbon Nanotubes for Medical Diagnosis and Therapy

Magnetic Nanoparticles for Diagnosis and Medical Therapy / Martin Sobik Sobik, Martin, Kirsten M. Pondman Pondman, Kirsten M., Ben Erné Erné, Ben, Bonny Kuipers Kuipers, Bonny, Bennie ten Haken Haken, Bennie ten, Horst Rogalla Rogalla, Horst 85

Feasibility of Magnetically Functionalised Carbon Nanotubes for Biological Applications: From Fundamental Properties of Individual Nanomagnets to Nanoscaled Heaters and Temperature Sensors / Matthias IS. Lutz Lutz, Matthias IS., Kamil Lipert Lipert, Kamil, Yulia Krupskaya Krupskaya, Yulia, Stefan Bahr Bahr, Stefan, Anja Wolter Wolter, Anja, Ahmed A. El-Gendy El-Gendy, Ahmed A., Silke Hampel Hampel, Silke, Albrecht Leonhardt Leonhardt, Albrecht, Arthur Taylor Taylor, Arthur, Kai Kramer Kramer, Kai, Bernd Buchner Buchner, Bernd, Rüdiger Klingeler Klingeler, Rüdiger 97

Nuclear Magnetic Resonance Spectroscopy and Imaging of Carbon Nanotubes / Vijay K. Anuganti Anuganti, Vijay K., Aldrik H. Velders Velders, Aldrik H. 125

Part III Interaction with Biological Systems

Exploring Carbon Nanotubes and Their Interaction with Cells Using Atomic Force Microscopy / Constanze Lamprecht Lamprecht, Constanze, Andreas Ebner Ebner, Andreas, Ferry Kienberger Kienberger, Ferry, Peter Hinterdorfer Hinterdorfer, Peter 153

Uptake, Intracellular Localization and Biodistribution of Carbon Nanotubes / V. Neves Neves, V., H. M. Coley Coley, H. M., J. McFadden McFadden, J., S. R. P. Silva Silva, S. R. P. 169

Recognition of Carbon Nanotubes by the Human Innate Immune System / Malgorzata J. Rybak-Smith Rybak-Smith, Malgorzata J., Kirsten M. M., Kirsten, Pondman, Emmanuel Flahaut Flahaut, Emmanuel, Carolina Salvador-Morales Salvador-Morales, Carolina, Robert B. Sim Sim, Robert B. 183

Toxicity and Environmental Impact of Carbon Nanotubes / E. Flahaut Flahaut, E. 211

Part IV Towards Targeted Chemotherapy and Gene Delivery

Carbon Nanotubes Loaded with Anticancer Drugs: A Platform for Multimodal Cancer Treatment / Elena Heister Heister, Elena, Vera Neves Neves, Vera, S. Ravi P. Silva Silva, S. Ravi P., Johnjoe McFadden McFadden, Johnjoe, Helen M. Coley Coley, Helen M. 223

Carbon Nanotubes Filled with Carboplatin: Towards Carbon Nanotube-Supported Delivery of Chemotherapeutic Agents / D. Haase Haase, D., S. Hampel Hampel, S., K. Kraemer Kraemer, K., D. Kunze Kunze, D., A. Taylor Taylor, A., M. Atit Atit, M., J. Thomas Thomas, J., S. Oswald Oswald, S., M. Ritschel Ritschel, M., R. Klingeler Klingeler, R., A. Leonhardt Leonhardt, A., B. Büchner Büchner, B. 247

Functionalized Carbon Nanotubes for Gene Biodelivery / V. Sanz-Beltrán Sanz-Beltrán, V., Ravi Silva Silva, Ravi, Helen Coley Coley, Helen, Johnjoe McFadden McFadden, Johnjoe 259.

Notes:

Includes bibliographical references and index.

ISBN:

9783642148019

3642148018

OCLC:

648933034