Critical pathways to success in CNS drug development / Neal R. Cutler ... [and others].

Format:

Book

Contributor:

Cutler, Neal R.

Language:

English

Subjects (All):

Neuropsychopharmacology.

Drug development.

Critical path analysis.

Central nervous system--Effect of drugs on--Research--Methodology.

Central Nervous System Agents--pharmacology.

Clinical Trials as Topic--methods.

Drug Evaluation--methods.

Drug Evaluation, Preclinical--methods.

Central nervous system--Effect of drugs on.

Research.

Methodology.

Central nervous system.

Medical Subjects:

Central Nervous System Agents--pharmacology.

Clinical Trials as Topic--methods.

Drug Evaluation--methods.

Drug Evaluation, Preclinical--methods.

Physical Description:

viii, 263 pages : illustrations ; 24 cm

Place of Publication:

Chichester, West Sussex, UK ; Hoboken, NJ : Wiley-Blackwell, 2010.

Contents:

The impending crisis in CNS drug development

Animal models and procedures for CNS disorders

Preclinical antecedents to early human clinical trials

Biomarkers and surrogate markers in drug development

Neuroimaging and cognitive assessments in early drug development

Bridging and CSF studies

A case study from preclinical to early clinical trials.

Notes:

Includes bibliographical references and index.

ISBN:

9781444330649

1444330640

OCLC:

434319490

Online:

Publisher description