Microarray methods for drug discovery / edited by Sridar V. Chittur.

Format:

Book

Contributor:

Chittur, Sridar V.

Series:

Methods in molecular biology (Clifton, N.J.) ; v. 632.

Methods in molecular biology, 1940-6029 ; 632

Language:

English

Subjects (All):

Drug development.

High throughput screening (Drug development).

Drug Discovery--methods.

Drug Evaluation, Preclinical--methods.

Microarray Analysis--methods.

Oligonucleotide Array Sequence Analysis.

Medical Subjects:

Drug Discovery--methods.

Drug Evaluation, Preclinical--methods.

Microarray Analysis--methods.

Oligonucleotide Array Sequence Analysis.

Physical Description:

xi, 284 pages : illustrations ; 27 cm.

Place of Publication:

New York, NY : Humana Press, [2010]

Contents:

1. Multicenter Clinical Sample Collection for Microarray Analysis / Tony S. Mondala, Daniel R. Salomon, and Steven R. Head

2. Isolation of Total RNA from Transgenic Mouse Melanoma Subsets Using Fluorescence-Activated Cell Sorting / Scott Tighe and Matthew A. Held

3. Microarray Analysis of Embryonic Stem Cells and Differentiated Embryoid Bodies / Alexander C. Zambon and Christopher S. Barker

4. Determination of Alternate Splicing Events Using the Affymetrix Exon 1.0 ST Arrays / Sita Subbaram, Marcy Kuentzel, David Frank, C. Michael DiPersio, and Sridar V. Chittur

5. Profiling microRNA Expression with the Illumina BeadChip Platform / Julissa Tsao, Patrick Yau, and Neil Winegarden

6. TaqMan® Array Cards in Pharmaceutical Research / David N. Keys, Janice K. Au-Young, and Richard A. Fekete

7. DMET Microarray Technology for Pharmacogenomics-Based Personalized Medicine / James K. Burmester, Marina Sedova, Michael H. Shapero, and Elaine Mansfield

8. The Use of Microarray Technology for Cytogenetics / Bassem A. Bejjani, Lisa G. Shaffer, and Blake C. Ballif

9. PCR/LDR/Universal Array Platforms for the Diagnosis of Infectious Disease / Maneesh Pingle, Mark Rundell, Sanchita Das, Linnie M. Golightly, and Francis Barany

10. RIP-CHIP in Drug Development / Ritu Jain, Francis Doyle, Ajish D. George, Marcy Kuentzel, David Frank, Sridar V. Chittur, and Scott A. Tenenbaum

11. ChIPing Away at Global Transcriptional Regulation / Kelly Jackson, James Paris, and Mark Takahashi

12. HELP (HpaII Tiny Fragment Enrichment by Ligation-Mediated PCR) Assay for DNA Methylation Profiling of Primary Normal and Malignant B Lymphocytes / Rita Shaknovich, Maria E. Figueroa, and Ari Melnick

13. High-Throughput Screening of Metalloproteases Using Small Molecule Microarrays / Mahesh Uttamchandani

14. Metabolic Enzyme Microarray Coupled with Miniaturized Cell-Culture Array Technology for High-Throughput Toxicity Screening / Moo-Yeal Lee, Jonathan S. Dordick, and Douglas S. Clark

15. Use of Tissue Microarray to Facilitate Oncology Research / Panagiotis Gouveris, Paul M. Weinberger, and Amanda Psyrri

16. Small Molecule Selectivity and Specificity Profiling Using Functional Protein Microarrays / Peter R. Kraus, Lihao Meng, and Lisa Freeman-Cook

1.7 Production and Application of Glycan Microarrays / Julia Busch, Ryan McBride, and Steven R. Head

Notes:

"Springer protocols"--Cover.

Includes bibliographical references and index.

ISBN:

9781607616627

1607616629

OCLC:

471801589