Esophageal pain / [edited by] Ravinder K. Mittal.

Format:

Book

Contributor:

Mittal, Ravinder K.

Language:

English

Subjects (All):

Heartburn.

Esophagus--Pathophysiology.

Esophagus.

Esophagus--Innervation.

Esophagus--physiopathology.

Pain.

Physiology, Pathological.

Medical Subjects:

Esophagus--physiopathology.

Heartburn.

Pain.

Physical Description:

xi, 180 pages : illustrations (some color) ; 27 cm

Place of Publication:

San Deigo : Plural Pub., [2010]

Summary:

MD, is a graduate of University of Delhi, India, and has been a resident of the United States since 1978. Following initial training in internal medicine and a three-year clinical and research fellowship in gastroenterology at Yale University, he became an Assistant Professor of Medicine and Director of Gastrointestinal Function Laboratory at the University of Virginia in Charlottesville, Virginia, in 1985. Dr. Mittal rose in ranks and stayed at UVA until 1997. For the last twelve years, he has been a Professor of Medicine at the University of California, San Diego in La Jolla, California. He is a passionate teacher, an empathetic clinician, and a keen investigator.

Ever since his first research project in 1983, "Identification and Mechanism of Delayed Acid Clearance in Hiatus Hernia," Dr. Mittal has remained a passionate translational investigator in the area of physiology and pathophysiology of esophagus. Author of more than 100 original publications and a large number of review articles and book chapters, he continues to unravel the mysteries of the esophagus. During the last twenty-five years of his investigative career, he has made number of seminal observations with regard to the role of crural diaphragm as an external lower esophageal sphincter, transient lower esophageal sphincter relaxation as the pathophysiologic mechanism of reflux diseases, and muscle hypertrophy in escophageal motor disorders. For more than ten years, he has keenly investigated the role of longitudinal muscles of the esophagus in health and diseases of esophagus. In 1995 he won the inaugural Janssen Awards in Gastroenterology. Considered to be one of the most important hallmarks of a true scientific investigator in medicine, Dr. Mittal's research has been funded continuously by the National Institute of Health since 1988.

Contents:

Heartburn and esophageal pain : scope of the problem / John Dent

Functional heartburn : what is it? / Ronnie Fass

Nature of esophageal pain receptors / Amanda J. Page and L. Ashley Blackshaw

Vagal and splanchnic distension sensitive primary afferents from the opossum esophagus : implications for visceral nociceptors / Raj K. Goyal and Arun Chaudhury

The esophageal mucosa and heartburn / Roy C. Orlando

Neutral reflux (weakly acid) in typical and atypical GERD symptoms / Daniel Sifrim

Longitudinal muscle spasm and esophageal pain / Ravinder K. Mittal

Biomechanics of esophageal sensation / Hans Gregersen and Asbjørn Mohr Drewes

Molecular pathways and their sensitization / Pankaj Jay Pasricha

Cortical processing of esophageal pain / Adeyemi Lawal and Reza Shaker

Esophageal hypersensitivity : is it peripheral or central? / A.bhishek Sharma and Qasim Aziz

Diagnostic strategy for esophageal pain / Peter J. Kahrilas

How to treat esophageal chest pain / Satish S.C. Rao

New drugs on the horizon for the treatment of esophageal pain / Anders Lehmann.

Notes:

Includes bibliographical references and index.

ISBN:

9781597563376

1597563374

OCLC:

229028550