Chronopharmaceutics : science and technology for biological rhythm-guided therapy and prevention of diseases / edited by Bi-Botti C. Youan.

Format:

Book

Contributor:

Youan, Bi-Botti C.

Language:

English

Subjects (All):

Drugs--Dosage forms.

Drugs.

Chronobiology.

Drug Chronotherapy.

Chronotherapy.

Medical Subjects:

Drug Chronotherapy.

Chronotherapy.

Physical Description:

xxxii, 341 pages, 8 unnumbered pages of plates : illustrations (partly color) ; 25 cm

Other Title:

Science and technology for biological rhythm-guided therapy and prevention of diseases

Place of Publication:

[Hoboken, N.J.] : Wiley, [2009]

Summary:

As we better understand how biological processes unfold in real time through advances in chronobiology and related fields, we can create safer, more effective drugs, drug delivery systems, and disease monitoring and prevention systems. When administered in correct coordination with a patient's body rhythms, such drugs can maximize therapeutic outcome while minimizing unwanted side effects. Chronopharmaceutics presents the first standard reference text on this emerging cross-disciplinary field and its potential for therapeutic and preventive medicine.

Bringing together the latest findings from experienced investigators, this edited work presents a much-needed single source on chronopharmaceutics. After an introduction that includes a timeline of key discoveries, an overview of regulatory, formulation, manufacturing and key resource issues associated with chronopharmaceutics, the detailed coverage examines:

Filling a gap in both the graduate classroom and the working industrial or research laboratory, Chronopharmaceutics offers students, instructors, and professionals a unique and comprehensive reference for this cutting-edge field.

Contents:

1 Overview of Chronopharamaceutics / Bi-Botti C. Youan 1

2 Chronogenetics / Franck Delaunay 51

3 Chronopharmacokinetics / Bernard Bruguerolle 79

4 Chemical Oscillator Systems For Chronotherapy / Steven A. Giannos 99

5 Diffucaps ʼ Technology for Controlled Release Drug Delivery / Gopi Venkatesh 121

6 ChronotopicTM Technology / M. E. Sangalli, A. Maroni, L. Zema, M. Cerea, A. Gazzaniga 145

7 Chronotherapy Using Egalet ʼ Technology / Daniel Bar-Shalom, Clive G. Wilson, Neena Washington 165

8 ChronsetTM: An Oros ʼ Delivery System for Chronotherapy / Liang C. Dong, Crystal Pollock-Dove, Patrick S.L. Wong 175

9 Controlled Release Microchips / Karen Daniel, Hong Linh Ho Duc, Michael Cima, Robert Langer 187

10 Implications and Applications of Circadian Susceptibility Rhythms: Chronomics and Anesthesia / Franz Halberg, Germaine Cornľissen, Othild Schwartzkopff 217

11 Treatment with Open Eyes: Markers-Guided Chronotheranostics / Germaine Cornľissen, Franz Halberg 257.

Notes:

Includes bibliographical references and index.

ISBN:

9780471743439

0471743437

OCLC:

310400038