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Erythropoietins, erythropoietic factors, and erythropoiesis : molecular, cellular, preclinical, and clinical biology / edited by Steven G. Elliott, MaryAnn Foote, and Graham Molineux.
Holman Biotech Commons QP96 .E792 2009
Available
- Format:
- Book
- Series:
- Milestones in drug therapy
- Language:
- English
- Subjects (All):
- Erythropoietin.
- Erythropoietin--Therapautic use.
- Erythropoiesis.
- Erythropoiesis--Molecular aspects.
- Anemia--Treatment.
- Anemia.
- Anemia--drug therapy.
- Erythropoietin, Recombinant--pharmacology.
- Erythropoietin, Recombinant--therapeutic use.
- Medical Subjects:
- Erythropoiesis.
- Anemia--drug therapy.
- Erythropoietin, Recombinant--pharmacology.
- Erythropoietin, Recombinant--therapeutic use.
- Physical Description:
- xviii, 326 pages : illustrations (partly color) ; 24 cm.
- Edition:
- Second revised and ext. edition.
- Place of Publication:
- Basel ; Boston : Birkhäuser, [2009]
- Summary:
- This second edition is a one-source guide to current information about red blood cell physiology and the action of native and recombinant human erythropoietic factors. Topics in the fields of erythropoiesis, recombinant protein discovery and production, treatment of patients with anemia, and abuse by certain athletes who wish to improve performance are covered. The newest theories in erythropoiesis (receptors, signaling), clearance, manufacturing, new formulations, and clinical research are discussed.
- This book is of interest to researchers and clinical investigators in academia and biotechnology and pharmaceutical companies, to clinical research associates, clinical monitors, and physician investigators.
- Contents:
- Erythropoiesis: an overview / B.E. Torbett and J.S. Friedman
- Regulation of endogenous erythropoietin production / D.R. Mole and P.J. Ratcliffe
- Biology of erythropoietin / G. Molineux and A.M. Sinclair
- Erythropoiesis-genetic abnormalities / J.T. Prchal and X.T. Gregg
- Studies of erythropoiesis and the discovery and cloning of recombinant human erythropoietin / M.A. Foote
- Commercial production of recombinant erythropoietins / A.S. Chuck ... [et al.]
- Biosimilar epoetins / H. Schellekens
- New molecules and formulations / S.G. Elliott
- Structural basis for the signal transduction of erythropoietin / T.D. Osslund
- Intracellular signaling by the erythropoietin receptor / H.F. Lodish ... [et al.]
- Mechanism of erythropoietin receptor activation / S.N. Constantinescu
- Pharmacokinetics of erythropoiesis-stimulating agents / S. Doshi ... [et al.]
- Use of erythropoietic stimulating agents in the setting of renal disease / D.A. Goodkin
- Abuse of recombinant erythropoietins and blood products by athletes / D.H. Catlin and C.K. Hatton
- Role and regulation of iron metabolism in erythropoiesis and disease / T.L. Arvedson and B.J. Sasu
- Nonhematopoietic effects of erythropoiesis-stimulating agents / W. Jelkmann, R. Depping and E. Metzen.
- Notes:
- Rev. ed. of: Erythropoietins and erythropoiesis : molecular, cellular, preclinical, and clinical biology / edited by G. Molineux, M.A. Foote, and S.G. Elliott. c2003.
- Includes bibliographical references and index.
- ISBN:
- 9783764386948
- 3764386940
- 3764386983
- 9783764386986
- OCLC:
- 339358819
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