Genome mapping and genomics in domestic animals / Noelle E. Cockett, Chittaranjan Kole (editors).

Format:

Book

Contributor:

Cockett, Noelle E.

Kole, Chittaranjan

Series:

Genome mapping and genomics in animals ; v. 3.

Genome mapping and genomics in animals ; v. 3

Language:

English

Subjects (All):

Domestic animals--Genome mapping.

Domestic animals.

Genomics.

Animals, Domestic--genetics.

Chromosome Mapping--veterinary.

Medical Subjects:

Animals, Domestic--genetics.

Chromosome Mapping--veterinary.

Genomics.

Physical Description:

xvi, 279 pages : illustrations (partly color) ; 27 cm.

Place of Publication:

Berlin ; London : Springer, 2009.

Summary:

Genomics research on animals has generated huge databases and several new concepts and strategies, which are used to elucidate origin, evolution and phylogeny of species. Genetic and physical maps of genomes give details on chromosomal location, function, expression and regulation of genes. The series Genome Mapping and Genomics in Animals provides comprehensive and up-to-date reviews on genomic research on selected animal systems contributed by leading scientists from around the world.

This volume offers information on gene mapping and genomics research in domesticated and farmed animals including cattle, water buffalo, sheep, deer, poultry, turkeys, rabbits, dogs and pigs. While the genome maps for some species are very limited, full genome sequences are available for cattle, chickens and dogs. Genomic research contributes to the identification of genetic regions that control the functionality and well-being of animals. Several farmed species are also used as models for biomedical studies.

Contents:

1 Cattle / M. D. MacNeil, J. M. Reecy, D. J. Garrick 1

1.1.1 History 1

1.1.2 Economic Importance 1

1.2 Molecular Genetics 3

1.2.1 Genetic-Mapping Resources 3

1.2.2 Quantitative Trait Loci 5

1.2.3 Using Genotypes in Breeding Cattle 8

1.3 Future Scope of Work 9

2 Water Buffalo / L. Iannuzzi, G. P. Di Meo 19

2.1.1 Taxonomic Description 19

2.1.2 Economic Importance 21

2.1.3 Breeding Objectives 22

2.2 Molecular Genetics 23

2.2.1 Classical Mapping Efforts 23

2.2.2 Construction of Genetic Maps and Comparative Mapping 24

2.3 Future Scope of Work 28

3 Sheep / C. A. Bidwell, N. E. Cockett, J. F. Maddox, J. E. Beever 33

3.1.1 Economic and Biomedical Importance 33

3.1.2 History 34

3.1.3 The Sheep Karyotype 34

3.2 Molecular Genetics 35

3.2.1 Linkage Maps 36

3.2.2 Mapped Traits in Sheep 36

3.2.3 Resources for Mapping and Sequencing the Ovine Genome 39

3.3 Future Scope of Work 41

4 Deer / Richard J. Hall 47

4.1.1 Taxonomic Description 47

4.1.2 Economic Importance 48

4.1.3 Karotype of Cervids 48

4.2 Molecular Genetics 48

4.2.1 Genetic Analysis Using Molecular Markers 48

4.2.2 The Deer Genetic Map 60

4.2.3 Genes 61

4.2.4 Quantitative Trait Loci in Deer 62

4.2.5 Chronic Wasting Disease of North American Cervids 65

4.3 Future Scope of Work 66

5 Poultry / Michael N. Romanov, Alexei A. Sazanov, Irina Moiseyeva, Aleksandr F. Smirnov 75

5.1.1 Brief History and Zoological Description 75

5.1.2 Chickens 77

5.1.3 Economic Importance and Nutritional Value 82

5.1.4 Breeding Objectives 85

5.2 Classic Genetics 86

5.2.1 Brief History of Poultry Genetics 86

5.2.2 Early Classical Mapping Efforts 86

5.2.3 First Chicken Map 99

5.2.4 Subsequent Classical Mapping 100

5.3 Molecular Genetics and Whole-Genome Sequence 101

5.3.1 First-generation Molecular Maps 101

5.3.2 Physical Maps 103

5.3.3 Whole-Genome Sequence 105

5.3.4 Chicken Genome and Sequence Features 107

5.3.5 Genetics and Molecular Mapping in Other Birds 110

5.4 QTL and Functional Genomics 120

5.4.1 QTL Analysis 120

5.4.2 QTL: Growth, Meat Quality, and Productivity 120

5.4.3 QTL: Egg Quality and Productivity 122

5.4.4 QTL: Disease Resistance 122

5.4.5 QTL: Behavior 123

5.4.6 Toward Functional Genomics of Poultry 123

5.5 Other Molecular Applications 124

5.5.1 Biodiversity Studies 124

5.5.2 Molecular Sexing 125

6 Turkey / Kent M. Reed 143

6.1.1 Origin and Domestication 143

6.1.2 Taxonomy and Zoological Description 144

6.1.3 Modern Breeding Objectives 144

6.1.4 Economic Importance 145

6.1.5 Karyotype and Genome 147

6.1.6 Classical Mapping Efforts and Limitations 147

6.2 Construction of Genetic Maps 148

6.2.1 Genetic Markers 148

6.2.2 Primary Genetic Linkage Maps 151

6.2.3 Second-generation Linkage Map 151

6.2.4 Integrative Mapping 153

6.2.5 Comparative Mapping 154

6.2.6 Other Comparative Studies 155

6.2.7 Physical Mapping 157

6.2.8 The Next-Generation Physical Maps 157

6.3 Advanced Works, Functional Genomics 158

6.3.1 ESTs, Microarrays, and SAGE 158

6.3.2 Candidate Gene Mapping 159

7 Rabbit / Claire Rogel-Gaillard, Nuno Ferrand, Helene Hayes 165

7.1.1 History 165

7.1.2 Taxonomic Position 165

7.1.3 Physical Characteristics 166

7.1.4 Breeds 166

7.1.5 Domestication, Phylogeny, and Genetic Diversity 167

7.1.6 Economic Importance 171

7.2 Molecular Genetics 175

7.2.1 Cytogenetics 175

7.2.2 Genetic Molecular Markers 176

7.2.3 Physical Mapping Tools 204

7.2.4 Sequencing Data 204

7.2.5 Bioinformatics Tools 205

7.2.6 Expected Tools and Development 206

7.2.7 Genome Mapping 206

7.3 Future Scope of Work 220

7.3.1 Using Rabbits to Study the Domestication Process 220

7.3.2 Using Rabbits to Study Color Patterns 220

7.3.3 Using Rabbits to Study Early Embryonic Development 220

7.3.4 Using Rabbits to Produce Embryonic Stem Cells and Validate Candidate Genes 221

7.3.5 Perspectives of the Rabbit as a Farm Animal 221

8 Dog / D.S. Mosher, T.C. Spady, E.A. Ostrander 231

8.1.1 Dog Breeds 231

8.1.2 Genetic Diversity and Dog Breeds 233

8.1.3 The Superfamily Canoidae 234

8.1.4 Mitochondrial DNA (MtDNA) Analysis of Canids 234

8.1.5 The Domestic Dog Population 236

8.2 Molecular Genetics of Dogs 237

8.2.1 Canine Linkage and Radiation Hybrid Maps 237

8.2.2 Comparative Maps 238

8.2.3 Survey Sequence and a Canine Gene Map 239

8.2.4 The 7.5x Canine Genome Sequence 240

8.2.5 Single Gene Traits 241

8.2.6 Complex Traits 244

8.3 Future Scope of Work 250

9 Pig / C.W. Ernst, A.M. Ramos 257

9.1.1 History and Description 257

9.1.2 Economic Importance 258

9.1.3 Breeding Objectives 258

9.2 Molecular Genetics of Pigs 259

9.2.1 Genetic Maps 259

9.2.2 Physical and RH Maps 260

9.2.3 Pig-Human Comparative Maps 260

9.2.4 Quantitative Trait Loci 261

9.2.5 Candidate Gene Discovery 262

9.2.6 Marker-Assisted Breeding 264

9.3 Functional Genomics 265

9.3.1 Expressed Sequence Tags 265

9.3.2 DNA Microarrays 265

9.4 Future Scope of Work 266

9.4.1 Swine Genome Sequencing 266

9.4.2 Expression QTL 266.

Notes:

Includes bibliographical references and index.

ISBN:

9783540738343

3540738347

OCLC:

233934774