Evidence-based diagnosis / Thomas B. Newman, Michael A. Kohn.

Format:

Book

Author/Creator:

Newman, Thomas B.

Contributor:

Kohn, Michael A.

Language:

English

Subjects (All):

Diagnosis.

Evidence-based medicine.

Function tests (Medicine)--Evaluation.

Function tests (Medicine).

Diagnosis--Research.

Diagnostic Techniques and Procedures.

Research.

Evaluation.

Clinical Medicine--methods.

Evidence-Based Medicine.

Medical Subjects:

Diagnostic Techniques and Procedures.

Clinical Medicine--methods.

Evidence-Based Medicine.

Physical Description:

xiii, 295 pages : illustrations ; 26 cm

Place of Publication:

Cambridge ; New York : Cambridge University Press, 2009.

Summary:

Evidence-Based Diagnosis is a textbook about diagnostic, screening, and prognostic tests in clinical medicine. The authors' approach is based on many years of experience teaching physicians in a clinical research training program. Although requiring only a minimum of mathematics knowledge, the quantitative discussions in this book are deeper and more rigorous than those in most introductory texts. The book includes numerous worked examples and 60 problems (with answers) based on real clinical situations and journal articles. The book will be helpful and accessible to anyone looking to select, develop, or market medical tests. Topics covered include:

The diagnostic process

Test reliability and accuracy

Likelihood ratios

ROC curves

Testing and treatment thresholds

Critical appraisal of studies of diagnostic, screening, and prognostic tests

Test independence and methods of combining tests

Quantifying treatment benefits using randomized trials and observational studies

Bayesian interpretation of P-values and confidence intervals

Challenges for evidence-based diagnosis

Contents:

Introduction: Understanding diagnosis and diagnostic testing

Reliability and measurement error

Dichotomous tests

Multilevel and continuous tests

Critical appraisal of studies of diagnostic tests

Screening tests

Prognostic tests and studies

Multiple tests and multivariable decision rules

Quantifying treatment effects using randomized trials

Alternatives to randomized trials for estimating treatment effects

Understanding P-values and confidence intervals

Challenges for evidence-based diagnosis.

Notes:

Includes bibliographical references and index.

ISBN:

9780521886529

052188652X

9780521714020

0521714028

OCLC:

262430881