Aquaporins / Eric Beitz, editor ; contributors, P. Agre ... [and others].

Format:

Book

Contributor:

Beitz, Eric.

Agre, Peter, 1949-

Series:

Handbook of experimental pharmacology ; v. 190.

Handbook of experimental pharmacology ; v. 190

Language:

English

Subjects (All):

Aquaporins.

Medical Subjects:

Aquaporins.

Physical Description:

xvi, 424 pages : illustrations (some color) ; 24 cm.

Place of Publication:

Berlin : Springer, [2009]

Contents:

Discovery of the Aquaporins and Development of the Field / Jennifer M. Carbery, Peter Agre 3

Part I Aquaporin Protein Structure and Selectivity Mechanisms

The AQP Structure and Functional Implications / Thomas Walz, Yoshinori Fujiyoshi, Andreas Engel 31

Dynamics and Energetics of Permeation Through Aquaporins. What do we Learn from Molecular Dynamics Simulations? / Jochen S. Hubn, Helmut Grubmüller, Bert L. de Groot 57

In Vitro Analysis and Modification of Aquaporin Pore Selectivity / Eric Beitz, Dana Becker, Julia von Büllow, Christina Conard, Nadine Fricke, Amornrat Geadkaew, Dawid Krenc, Jie Song, Dorothea Wree, Binghua Wu 77

Part II Aquaporin Function in Mammalian Water Homeostasis

Aquaporins in the Kidney / Tae-Hwan Kwon, Jakob Nielsen, Hanne B. Mφller, Robert A. Fenton, Sφren Nielsen, Jφrgen Frφgen Frφkiær 95

Regulation of Aquaporin-2 Trafficking / Pavel I. Nedvetsky, Grazia Tamma, Sven Beulshausen, Giovanna Valenti, Walter Rosenthal, Enno Klussmann 133

Role of Aquaporin-4 in Cerebral Edema and Stroke / Zsolt Zador, Shirley Stiver, Vincent Wang, Geoffrey T. Manley 159

Aquaporins as Potential Drug Targets for Meniere's Disease and its Related Diseases / Tazio Takeda, Daizo Taguchi 171

Aquaporins in Secretory Glands and their Role in Sjögren's Syndrome / Christine Delporte 185

Part III Aquaporin Glycerol Permeability in Mammalian Physiology

Skin Aquaporins: Function in Hydration, Wound Healing, and Skin Epidermis Homeostasis / Mathieu Boury-Jamot, Jean Daraspe, Frédéric Boneté, Eric Perrier, Sylvianne Schnebert, Marc Dumas, Jean-Marc Verbavatz 205

Function of Aquaporin-7 in the Kidney and the Male Reproductive System / Eisei Sohara, Shinichi Uchida, Sei Sasaki 219

Role of Aquaporin-7 and Aquaporin-9 in Glycerol Metabolism; Involvement in Obesity / Norikazu Maeda, Toshiyuki Hibuse, Tohru Funahashi 233

New Members of Mammalian Aquaporians: AQP10-AQP12 / Kenich Ishibashi 251

Part IV Aquaporin Functions Apart from Water and Glycerol Transport

Structural Function of MIP/Aquaporin 0 in the Eye Lens; Genetic Defects Lead to Congenital Inherited Cataracts / Ana B. Chepelinsky 265

pH Regulated Anion Permeability of Aquaporin-6 / Masato Yasui 299

Aquaglyceroporins and Metalloid Transport: Implications in Human Diseases / Hiranmoy Bhattacharjee, Barry P. Rosen, Rita Mukhopadhyay 309

Ammonia and Urea Permeability of Mammalian Aquaporins / Thomas Litman, Rikke Sφgaard, Thomas Zeuthen 327

Knock-Out Models Reveal New Aquaporin Functions / Alan S. Verkman 359

Part V Towards Therapeutic Use of Aquaporins

Design, Synthesis and Assaying of Potential Aquaporin Inhibitors / Rose Haddoub, Michael Rützler, Aélig Robin, Sabine L. Flitsch 385

Aquaporin-1 Gene Transfer to Correct Radiation-Induced Salivary Hypofunction / Bruce J. Baum, Changyu Zheng, Ana P. Cotrim, Linda McCullagh, Corinne M. Goldsmith, Jaime S. Brahim, Jane C. Atkinson, R. James Turner, Shuying Liu, Nikolay Nikolov, Gabor G. Illei 403.

Notes:

Includes bibliographical references and index.

ISBN:

9783540798842

3540798846

3540798854

9783540798859

OCLC:

297796510