Frontiers of cord blood science / Niranjan Bhattacharya, Phillip Stubblefield, editors ; foreword by Eliane Gluckman.

Format:

Book

Contributor:

Bhattacharya, Niranjan.

Stubblefield, Phillip G.

Language:

English

Subjects (All):

Fetal blood--Therapeutic use.

Fetal blood.

Stem cells--Transplantation.

Stem cells.

Fetal Blood--transplantation.

Stem Cell Transplantation.

Medical Subjects:

Fetal Blood--transplantation.

Stem Cell Transplantation.

Physical Description:

xxix, 374 pages : illustrations (some color) ; 25 cm

Place of Publication:

London : Springer, [2009]

Summary:

Since the first successful transplantation of umbilical cord blood in 1988, cord blood has become an important source of hematopoietic stem and progenitor cells for the treatment of blood and genetic disorders. Significant progress has been accompanied by challenges for scientists, ethicists, and health policy makers. With the recognition of the need for a national system for the collection, banking, distribution, and use of cord blood and the increasing focus on cord blood as an alternative to embryos as a source of tissue for regenerative medicine, it has garnered significant attention recently.

Frontiers in Cord Blood Science contains chapters from distinguished investigators currently engaged in researching cord blood in the treatment of various diseases of the brain, heart, liver, pancreas, bone, and cartilage. It presents the current state of research in the field and discusses the potential future applications of cord blood for the research and treatment of various diseases and conditions. In addition, the book reviews the possibility for novel uses in surgical wound healing and in synthetic grafts for reconstructive surgery, allowing their better adhesion.

Investigating the ethical issues, this book will be of interest to all scientists and researchers within the field of regenerative medicine and also clinicians in dermatology, neurology, cardiology, and orthopedics who wish to discover more about the potential for the revolutionary medical approach of human umbilical cord blood.

Contents:

Section I Umbilical Cord Blood Stem Cell (Basic Science)

1 Placental and Pregnancy Stem Cells / Anjali Mehta, Curtis Cetrulo, Phillip Stubblefield, Kyle Cetrulo 3

2 Cord Blood Stem Cells - The Basic Science / Peter Hollands 19

3 Stem Cells from Umbilical Cord Blood / Patricia Pranke, Raquel Canabarro 27

4 Ex Vivo Expansion of Cord Blood / Ian K. McNiece, Elizabeth J. Shpall 91

5 Mesenchymal Stem Cells: Applications in Cell and Gene Therapy / Pablo Bosch, Steven L. Stice 97

6 Non-hematopoietic Stem and Progenitor Cells Derived From Human Umbilical Cord Blood / Karen Bieback, Harald Kluter 123

Section II Umbilical Cord Blood Stem Cell Transplantation

7 Cord Blood Transplantation for Pediatric Non-Malignant Conditions / Tatjana Kilo, Peter J. Shaw 161

8 Cord Blood Transplantation for Hematologic Malignancies / Karen Quillen 195

9 Double Umbilical Cord Blood Transplantation in Adults / Karen K. Ballen 209

Section III Transfusion of Cord Blood

10 Placental Umbilical Cord Whole Blood Transfusion: A True Blood Substitute to Combat Anemia in the Background of Chronic Disease - A Study Report (1999-2006) / Niranjan Bhattacharya 227

11 Umbilical Cord Blood Therapy in Neurology / Abhijit Chaudhuri, Niranjan Bhattacharya 265

12 Cord Blood: Opportunities and Challenges for the Reconstructive Surgeon / Andrew Burd, T. Ayyappan, Lin Huang 273

13 Umbilical Cord Blood Transfusion - A Clinical Overview / Himansu Kumar Basu 289

Section IV Cord Blood Stem Cell Banking

14 Establishment of the UK Stem Cell Bank and Its Role in Stem Cell Science / G.N. Stacey 299

15 Cord Blood Allogeneic and Autologous Banking / Carolyn Troeger, Wolfgang Holzgreve 307

Section V Potential Engineering Application of Cord Blood

16 Possibilities of Using Cord Blood for Improving the Biocompatibility of Implants / K. Kaladhar, Chandra P. Sharma 319

17 Potential of Stem Cell to Tailor the Bone-Ceramic Interface for Better Fixation of Orthopedic Implants / Jui Chakraborty, Debabrata Basu 331

Section VI Ethics

18 Some Aspects of the Ethics of Stem Cell Research / Ranes C. Chakravorty 361.

Notes:

Includes bibliographical references and index.

ISBN:

9781848001664

1848001665

1848001673

9781848001671

OCLC:

213384159