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The biology of gastric cancers / Timothy C. Wang, James G. Fox, Andrew S. Giraud, editors.
Holman Biotech Commons RC280.D5 B56 2009
By Request
- Format:
- Book
- Language:
- English
- Subjects (All):
- Stomach--Cancer--Pathophysiology.
- Stomach.
- Stomach--Cancer--Molecular aspects.
- Stomach--Cancer--Genetic aspects.
- Stomach Neoplasms--physiopathology.
- Stomach Neoplasms--genetic aspects.
- Stomach--Cancer.
- Medical Subjects:
- Stomach Neoplasms--physiopathology.
- Stomach Neoplasms--genetic aspects.
- Physical Description:
- xxii, 646 pages, 12 unnumbered pages of plates : illustrations (partly color), portraits ; 25 cm
- Place of Publication:
- New York ; London : Springer, [2009]
- Summary:
- There have been many impressive advances in our understanding of the pathogenesis of gastric adenocarcinoma, gastric MALT lymphoma, gastrointestinal stromal tumors of the stomach, and gastric carcinoid tumors over the years. The Biology of Gastric Cancers, edited by Dr. Timothy Wang, Dr. James Fox and Dr. Andy Giraud, pays homage to the cutting edge concepts of cancer stem cells, tumor microenvironment, chronic inflammation, and genetic susceptibility to cancer and represents the very first volume devoted to the subject of the basic biology of gastric cancer. With an emphasis on animal models, but also considerable attention to human studies, host genetics and the role of bacterial factors and other environmental factors influencing the pathogenesis of gastric cancer, the topics presented in this book should be of interest to clinicians and investigators interested in gastrointestinal cancer, as well as basic investigators in related areas of cancer research. This body of work will hopefully stimulate clinical and translational studies that will advance early diagnosis and treatment of gastric tumors.
- Contents:
- 1 Overview and Pathology of Gastric Cancer / Pelayo Correa, M. Constanza Camargo, M. Blanca Piazuelo 1
- 2 Epidemiology of Gastric Cancer and Helicobacter pylori / Jonathan Volk, Julie Parsonnet 25
- 3 Diet and Gastric Cancer / Chun Liu, Xiang-Dong Wang, Robert M. Russell 59
- 4 MALT Lymphoma: Clinicopathologic Features and Molecular Pathogenesis / Anne Muller 91
- 5 Gastrointestinal Stromal Tumors of Gastric Origin / Chandrajit P. Raut, Jason L. Hornick, Monica M. Bertagnolli 135
- 6 Human Gastric Neuroendocrine Neoplasia: Current Pathologic Status / Guido Rindi, Enrico Solcia 165
- 7 Gastric Neuroendocrine Neoplasia / Irvin M. Modlin, Mark Kidd, Maximillian V. Malfertheiner, Bjorn I. Gustafsson 185
- 8 Epstein-Barr Virus and Gastric Cancer / Ming-Shiang Wu, Chia-Tung Shun, Jaw-Town Lin 217
- 9 Role of Host Genetic Susceptibility in the Pathogenesis of Gastric Cancer / Emad M. El-Omar 235
- 10 Cancer Genetics of Human Gastric Adenocarcinoma / Roman Galysh, Jr., Steven M. Powell 251
- 11 Genomic and Proteomic Advances in Gastric Cancer / Alex Boussioutas, Patrick Tan 285
- 12 Animal Models of Gastric Carcinoma / Arlin B. Rogers, James G. Fox 323
- 13 Insights into the Development of Preneoplastic Metaplasia: Spasmolytic Polypeptide-Expressing Metaplasia and Oxyntic Atrophy / James R. Goldenring, Sachiyo Nomura 361
- 14 Deregulation of E-Cadherin in Precancerous Lesions and Gastric Cancer / Annie On On Chan, Benjamin Chun-Yu Wong 377
- 15 Role of CagA in Helicobacter pylori Infection and Pathology / Takeshi Azuma 389
- 16 The Role of Helicobacter pylori Virulence Factors in Rodent and Primate Models of Disease / Dawn A. Israel, Richard M. Peek, Jr. 403
- 17 Host Immunity in the Development of Gastric Preneoplasia / Peter B. Ernst, Mohammad S. Alam, Asima Bhattacharyya, Sheila E. Crowe 425
- 18 Atrophy and Altered Mesenchymal-Epithelial Signaling Preceding Gastric Cancer / Juanita L. Merchant, Yana Zavros 449
- 19 Genetic Models of Gastric Cancer in the Mouse / Andrew S. Giraud, Louise M. Judd 483
- 20 Prostaglandin and Transforming Growth Factor [beta] Signaling in Gastric Cancer / Masanobu Oshima, Hiroko Oshima, Makoto Mark Taketo 513
- 21 REG Proteins and Other Growth Factors in Gastric Cancer / Hirokazu Fukui, Yoshikazu Kinoshita, Tsutomu Chiba 541
- 22 Role of Bone Marrow-Derived Cells in Gastric Adenocarcinoma / JeanMarie Houghton, Timothy C. Wang 561
- 23 Stromal Cells and Tumor Microenvironment / Andrea Varro 587
- 24 Future Prospects for Helicobacter pylori Vaccination / Dominique Velin, Pierre Michetti 601.
- Notes:
- Includes bibliographical references and index.
- ISBN:
- 9780387691817
- 0387691812
- OCLC:
- 227916871
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