Hematopoietic stem cell transplantation / edited by Robert J. Soiffer.

Format:

Book

Contributor:

Soiffer, Robert J.

Series:

Contemporary hematology

Language:

English

Subjects (All):

Hematopoietic stem cells--Transplantation.

Hematopoietic stem cells.

Hematopoietic stem cell disorders--Treatment.

Hematopoietic stem cell disorders.

Hematopoietic Stem Cell Transplantation.

Medical Subjects:

Hematopoietic Stem Cell Transplantation.

Physical Description:

xvi, 736 pages : illustrations ; 26 cm.

Edition:

Second edition.

Place of Publication:

Totowa, N.J. : Humana, [2008]

Summary:

Remarkable developments in the field of hematopoietic stem cell transplantation have created opportunities to address the formidable challenges of histocompatibility barriers, stem cell expansion, therapy-related complications, and generation of graft-versus-host activity. Hematopoietic Stem Cell Transplantation, Second Edition, provides insight into these obstacles to success, and explores potential future applications of bone marrow-derived stem cells in the field of cardiac repair. New chapters introduce the biologic underpinnings of hematopoietic cell transplantation, and include contributions on basic stem cell biology, immunobiology, and histocompatibility. Written by experts in the field, Hematopoietic Stem Cell Transplantation, Second Edition provides the seasoned professional and student alike with a complete understanding of the current state of transplantation biology with an emphasis on indications for and results of transplantation in specific diseases.

Contents:

I Biology of Transplantation

1 Stem Cell Biology / Elizabeth O. Hexner, Stephen G. Emerson 3

2 Stem Cell Transplantation for Hematologic Malignancies / Effie W. Petersdorf 19

3 Immunobiology of Transplantation / Robert S. Negrin 39

II Transplantation for Specific Disorders

4 Allogeneic and Autologous Hematopoietic Stem Cell Transplantation for Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia in the Adult / Anthony Stein, Stephen J. Forman 57

5 Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia / Uday Popat, Sergio Giralt 83

6 Stem Cell Transplantation for Hodgkin's and Non-Hodgkin's Lymphomas / John W. Sweetenham 105

7 Transplantation in Chronic Lymphocytic Leukemia / Rifca Le Dieu, John G. Gribben 137

8 Stem Cell Transplantation in Multiple Myeloma / John Koreth, Kenneth C. Anderson 149

9 Allogeneic Hematopoietic Cell Transplantation for Patients with Myelodysplastic Syndrome and Myeloproliferative Disorders / Aravind Ramakrishnan, H. Joachim Deeg 167

10 Stem Cell Transplantation for Marrow Failure / Philippe Armand, Joseph H. Antin 183

11 Stem Cell Transplantation for Hemoglobinopathies / Catherine J. Wu 201

III Alternative Stem Cell Sources

12 Stem Cell Sources for Allogeneic Transplantation / Corey Cutler 225

13 Allogeneic Unrelated Donor Blood and Marrow Transplantation / Daniel Weisdorf 245

14 Umbilical Cord Hematopoietic Stem Cell Transplantation / Mitchell E. Horwitz, Nelson Chao 267

15 Haploidentical Stem Cell Transplantation / Bimalangshu R. Dey, Thomas R. Spitzer 289

IV Conditioning Regimens

16 Ablative Preparative Regimens for Hematopoietic Stem Cell Transplantation / Amin Alousi, Marcos de Lima 321

17 Nonmyeloablative Transplantation / Frederic Baron, Brenda M. Sandmaier 349

V Complications of Transplantation

18 Immune Reconstitution after Allogeneic Transplantation / Carolyn A. Keever-Taylor 377

19 Infection in the Hematopoietic Stem Cell Transplant Recipient / Francisco M. Marty, Lindsey R. Baden 421

20 EBV Lymphoproliferative Disease after Transplantation / Stephen Gottschalk, Cliona M. Rooney, Helen E. Heslop 449

21 Hepatic Veno-Occlusive Disease / Erica Linden, Paul Richardson 467

22 Lung Injury after Hematopoietic Stem Cell Transplantation / Kenneth R. Cooke, Gregory Yanik 495

23 Quality of Life Issues Post-Transplantation / Stephanie J. Lee 537

VI Graft-versus-Host Disease

24 Pathophysiology of Acute Graft-versus-Host Disease / Pavan Reddy, James L. M. Ferrara 563

25 Acute Graft-versus-Host Disease / Martin Benesch, H. Joachim Deeg 589

26 Chronic Graft-versus-Host Disease / Javier Bolanos-Meade, Georgia B. Vogelsang 621

VII Immune Modulation

27 Graft Manipulation: T Cell Depletion and Tumor Cell Purging / Vincent T. Ho 653

28 Donor Lymphocyte Infusions: Clinical Applications and the Graft-versus-Leukemia Effect / Edwin P. Alyea 687

VIII Future Uses of Hematopoietic Stem Cells

29 Regenerative Medicine: Application in Cardiovascular Diseases / Emerson C. Perin, Guilherme V. Silva, Marlos R. Fernandes 713.

Notes:

Includes bibliographical references and index.

ISBN:

9781934115053

1934115053

OCLC:

288986754