Stem cell research and therapeutics / Yanhong Shi, Dennis O. Clegg, editors.

Format:

Book

Contributor:

Shi, Yanhong.

Clegg, Dennis Owen.

Series:

Advances in biomedical research ; 1.

Advances in biomedical research ; 1

Language:

English

Subjects (All):

Stem cells.

Stem cells--Research.

Stem Cells.

Medical Subjects:

Stem Cells.

Physical Description:

xvii, 326 pages, 36 unnumbered pages of plates : illustrations (partly color) ; 25 cm.

Place of Publication:

[Dordrecht] : Springer, [2008]

Summary:

This book is an updated reference for one of the most exciting fields of biomedical research-Stem Cell Research and its therapeutic applications. Stem cell research holds great promise for the treatment of many human diseases that currently lack effective therapies. The set of chapters in this book provide insights into both basic stem cell biology and clinical applications of stem cell-based cell replacement therapies for a variety of human diseases, including cardiovascular diseases, neurological disorders, and liver degeneration. It also covers novel technologies for the culture and differentiation of both human embryonic stem cells and adult tissue stem cells. This book summarizes our current state of knowledge in stem cell research and integrates basic stem cell biology with regenerative medicine in an overall context. It is an essential reference for students, research fellows, academic and industrial scientists, and clinicians.

Contents:

1 Retinal Pigment Epithelial Cells: Development In Vivo and Derivation from Human Embryonic Stem Cells In Vitro for Treatment of Age-Related Macular Degeneration / Dennis O. Clegg, David Buchholz, Sherry Hikita, Teisha Rowland, Qirui Hu, Lincoln V. Johnson 1

2 Progenitor Cell Transplantation for Retinal Disease / Henry J. Klassen 25

3 Negative Regulation of Endogenous Stem Cells in Sensory Neuroepithelia: Implications for Neurotherapeutics / Jason A. Hamilton, Crestina L. Beites, Kimberly K. Gokoffski, Piper L. W. Hollenbeck, Shimako Kawauchi, Rosaseyla Santos, Alexandre Bonnin|cHsiao-Huei Wu, Joon Kim, Anne L. Calof 45

4 Epigenetic Control of Neural Stem Cell Self-Renewal and Specification / GuoQiang Sun, Chunnian Zhao, Yanhong Shi 69

5 Neural Stem Cells and Neurogenic Niche in the Adult Brain / Xuekun Li, Basam Z. Barkho, Xinyu Zhao 83

6 Progressing Neural Stem Cell Lines to the Clinic / Kenneth Pollock, John D. Sinden 105

7 Human Neural Stem Cells for Biopharmaceutical Applications / Lilian Hook, Norma Fulton, Gregor Russell, Timothy Allsopp 123

8 The Analysis of MicroRNAs in Stem Cells / Loyal A. Goff, Uma Lakshmipathy, Ronald P. Hart 141

9 Optimized Growth of Human Embryonic Stem Cells / Matthew A. Singer, Jacqui Johnson, Paul Bello, Robert Kovelman, Michelle Greene 169

10 Potential of Stem Cells in Liver Regeneration / Madhava Pai, Natasa Levicar, Nagy Habib 181

11 Cell Transplantation Therapy for Myocardial Repair: Current Status and Future Challenges / Wangde Dai, Robert A. Kloner 193

12 Surgical Stem Cell Therapy for the Treatment of Heart Failure / Federico Benetti, Luis Geffner, Daniel Brusich, Agustin Fronzutti, Roberto Paganini, Juan Paganini, Amit Patel 213

13 Use of Combinatorial Screening to Discover Protocols That Effectively Direct the Differentiation of Stem Cells 227

14 Adult Stem Cell Therapies for Tissue Regeneration: Ex Vivo Expansion in an Automated System / Kristin L. Goltry, Douglas M. Smith, James E. Dennis, Jon A. Rowley, Ronnda L. Bartel 251

15 The Hair Follicle Stem Cell as the Paradigm Multipotent Adult Stem Cell / Robert M. Hoffman 275.

Notes:

Includes bibliographical references and index.

ISBN:

9781402085017

140208501X

1402085028

9781402085024

OCLC:

233264239