Handbook of human immunology / edited by Maurice R. G. O'Gorman, Albert D. Donnenberg.

Format:

Book

Contributor:

O'Gorman, Maurice R. G.

Donnenberg, Albert David.

Language:

English

Subjects (All):

Immune system.

Immunology.

Immunity.

Immune System Diseases.

Immunologic Techniques.

Immunologic Tests.

Medical Subjects:

Immunity.

Immune System Diseases.

Immunologic Techniques.

Immunologic Tests.

Physical Description:

xv, 623 pages : illustrations ; 25 cm

Edition:

Second edition.

Other Title:

Human immunology

Place of Publication:

Boca Raton : CRC Press, [2008]

Summary:

Since the publication of the first edition of the Handbook of Human Immunology a decade ago, major scientific achievements have directly contributed to an increased understanding of the complexities of the human immune system in health and disease. Whether as a result of the sequencing of the entire human genome, or of technological advancements, several new components of the immune system have been revealed, along with new technologies for their measurement and evaluation.

Similar in format to the bestselling original, this edition of the Handbook of Human Immunology begins with an overview of the immune system. It then includes a discussion on statistics in immunological testing, delves into clinically relevant immunological parameters, and clarifies the basic principles underlying immune system assays, and applications and interpretations of immune tests.

Featuring Six New Chapters and Contributions from Twelve New Authors, the Handbook of Human Immunology, Second Edition- Explores the significant components of the innate and adaptive human immune system, Describes specific human conditions and contemporary methods for assessing them, Analyzes the relevance of specific measurements and potential pitfalls involved in their interpretation, Provides a useful, up-to-date reference for laboratory evaluation of the immune system and immune disorders, Emphasizes the molecular basis of normal and pathological immune responses, Includes new information on cell receptors, accessory molecules, cytokines, growth factors, and interleukins, along with their application in diagnosing and monitoring various diseases.

This new edition provides several new tables including two that cover more than double the number of recognized "clusters of differentiation" (CD's) on the surface of leukocytes and associated cells than the first edition of the Handbook. New chapters include practical discussions on the statistics of immunological testing, guidelines for CD4 testing in HIV infection, measurements of cytokines, characterization of the T cell repertoire, and a comprehensive treatise of immunological components and autoimmune disease in the gastrointestinal tract, among other up-to-date immunological tests and diseases.

Contents:

Overview of immunity / James D. Folds

Statistics of immunological testing / Albert D. Donnenberg

Human immunoglobulins / Robert G. Hamilton

The complement system / Patricia C. Giclas

Cellular immunology: monitoring of immune therapies / Theresa L. Whiteside

Understanding clinical flow cytometry / Albert D. Donnenberg and Vera S. Donnenberg

Leukemia and lymphoma immunophenotyping and cytogenetics / Maria A. Proytcheva

Guidelines for the use of flow cytometry in the management of patients infected with the human immunodeficiency virus type-1 and the acquired immunodeficiency syndrome / Maurice R.G. O'Gorman

Role of flow cytometry in the diagnosis and monitoring of primary immunodeficiency disease / Maurice R.G. O'Gorman

Detection and characterization of the T-cell receptor repertoire / Gulbu Uzel

Human leukocyte differentiation antigens, cluster of differentiation: past, present, and future / Maurice R.G. O'Gorman

Immunologic diagnosis of autoimmunity / Noel R. Rose

Autoimmune and immune-mediated diseases of the gastrointestinal tract / Stefano Guandalini, Mala Setty, and Bana Jabri

Serologic testing for infectious diseases / John L. Schmitz

Molecular techniques applied to infectious diseases / Jennifer S. Goodrich and Melissa B. Miller

Cytokines: regulators of immune responses and key therapeutic targets / Barbara Detrick, Chandrasekharam N. Nagineni, and John J. Hooks

Measuring human cytokines / Holden T. Maecker

The human major histocompatibility complex and DNA-based typing of human leukocyte antigens for transplantation / Susana G. Marino, Andrés Jaramillo, and Marcelo A. Fernández-Viña

Relevance of antibody screening and crossmatching in solid organ, hematopoietic stem cell transplantation, and blood transfusion / Chee L. Saw ... [et al.]

Functional assessment of immunosuppression: monitoring posttransplant alloreactivity with flow cytometric mixed lymphocyte cocultures / Chethan Ashok Kumar ... [et al.].

Notes:

Includes bibliographical references and index.

ISBN:

9780849319846

0849319846

OCLC:

166454325

Online:

Publisher description