Clinical challenges in lipid disorders / edited by Peter P. Toth and Domenic A. Sica ; [foreword by Scott M. Grundy].

Format:

Book

Contributor:

Toth, Peter P.

Sica, Domenic A.

Series:

Clinical challenges.

Clinical challenges

Language:

English

Subjects (All):

Lipids--Metabolism--Disorders.

Lipids.

Lipid Metabolism Disorders.

Medical Subjects:

Lipid Metabolism Disorders.

Physical Description:

xii, 297 pages : illustrations ; 25 cm.

Other Title:

Clinical challenges : Lipid disorders

Lipid disorders

Place of Publication:

Oxford ; Ashland OH : Clinical Pub., 2008.

Summary:

Lipid disorders are highly heterogeneous and widely prevalent throughout the world. Dyslipidemia is an important risk factor for atherosclerotic disease and its clinical sequelae, including myocardial infarction, ischemic stroke, and death. The impact of dyslipidemia treatment on risk for cardiovascular disease is one of the most intensively studied issues in all of medicine. This volume is an innovative approach to the identification and management of lipid disorders. Organized as a series of questions, each chapter presents a detailed yet accessible discussion of the problems posed. The questions discussed are among the most frequently encountered at both primary care and specialty conferences throughout the world. Carefully weighing the risks and benefits of specific therapies, the ensuing discourse presents a fair, balanced approach to conceptual controversies as well as exploring the diagnostic and therapeutic dilemmas that may arise.

This book is designed for the busy clinical practitioner who is in search of authoritative discussion that is balanced by evidencebased, best practice recommendations. It is intended as a resource for practitioners of primary care, cardiology, and endocrinology.

Contents:

1 How well do various lipids and lipoprotein measures predict cardiovascular disease morbidity and mortality? / K. C. Maki, M. R Dicklin 1

2 Framingham risk scoring or risk factor counting: which is more sensitive and how do I use this information to determine patient-specific lipid goals? / N. J. Stone, D. M. Lloyd-Jones 17

3 What is the metabolic syndrome, how do I treat it and is it a high-risk condition? / K. L. Wyne 27

4 Should all patients admitted to the hospital with an acute coronary syndrome initiate statin therapy? / J. A. Farmer, P. H. Jones 41

5 What are CAD risk equivalents and how did these clinical entities come to be so defined? / C. Marske, M. Clearfield 51

6 When should children and adolescents be screened for dyslipidemia and how should they be treated? / J. A. Brothers, S. R. Daniels 61

7 Management of dyslipidemia in women / R. Gadi, E. A. Meagher 75

8 In high and very high-risk patients, is it true that when it comes to LDL-c, lower is better and can a serum LDL-c be driven too low? / W. B. Borden, M. H. Davidson 89

9 How should we approach to statin-treated patient with myalgia? / C. R. Harper, T. A. Jacobson 101

10 Pleiotropic effects of statins and their relevance to cardiovascular outcomes / J. K. Liao 113

11 An update on the 'rubber chicken' treatment of dyslipidemia: therapeutic lifestyle change and the alphabet soup of behavior modification / M. A. Denke 125

12 What is the best place for fibrate therapy in reducing cardiovascular risk? / J. M. McKenney 137

13 Niacin for dyslipidemia management and atheroprevention: why, when and how? / E. A. Brinton 157

14 Which dietary supplements have proven efficacy for impacting serum lipids and cardiovascular outcomes and are any vitamins harmful to the cardiovascular system? / H. I. Katcher, Y. Cao, J. Zhang, P. M. Kris-Etherton 167

15 Why do lipid-lowering agents affect serum transaminase levels, are these drugs toxic to the liver and can they precipitate liver failure? / P. Puri, A. J. Sanyal 189

16 Should we treat a low serum HDL-c and what specific lifestyle changes and drugs can be used to raise a low HDL-c? / J. A. Farmer, A. M. Gotto, Jr 203

17 What is familial hypercholesterolemia and how should it be treated? / P. M. Moriarty, C. A. Gibson, J. M. Backes 219

18 Should plasma levels of lipoprotein(a) be measured? Guiding principles from bench to bedside / M. L. Koschinsky, S. M. Marcovina 235

19 Clinical utilization of advanced lipid testing / W. C. Cromwell 249

20 Should we treat dyslipidemia in the elderly and is there an upper age limit to instituting lipid-lowering therapy? / J. G. Robinson 261.

Notes:

Includes bibliographical references and index.

ISBN:

9781846920295

1846920299

OCLC:

174130919