2 options
Molecular biology of cancer : mechanisms, targets, and therapeutics / Lauren Pecorino.
Holman Biotech Commons RC269 .P436 2008
By Request
- Format:
- Book
- Author/Creator:
- Pecorino, Lauren.
- Language:
- English
- Subjects (All):
- Cancer--Molecular aspects.
- Cancer.
- Cancer cells.
- Neoplasms--etiology.
- Antineoplastic Agents--therapeutic use.
- Cell Transformation, Neoplastic--genetics.
- Neoplasms--genetics.
- Neoplasms--therapy.
- Medical Subjects:
- Neoplasms--etiology.
- Antineoplastic Agents--therapeutic use.
- Cell Transformation, Neoplastic--genetics.
- Neoplasms--genetics.
- Neoplasms--therapy.
- Physical Description:
- xviii, 316 pages, 4 unnumbered pages of plates : illustrations (partly color) ; 25 cm
- Edition:
- Second edition.
- Place of Publication:
- Oxford ; New York : Oxford University Press, 2008.
- Summary:
- Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics presents a fresh approach to the study of the molecular basis of cancer. Shows how an understanding of the molecular processes underpinning cancer can be directly applied to the development of new therapeutics, giving students a clear appreciation of how the theory translates to tackling the disease, Provides a carefully structured overview of the molecular mechanisms that regulate cell growth, and relates defects in these mechanisms to the onset of cancer, so that students can clearly see the link between the two, Draws on the latest research in this dynamic field and presents it with a unique clarity, making cutting-edge science readily accessible to students.
- Contents:
- DNA structure and stability: mutations versus repair
- Regulation of gene expression
- Growth factor signaling and oncogenes
- The cell cycle
- Growth inhibition and tumor suppressor genes
- Apoptosis
- Stem cells and differentiation
- Metastasis
- Infections and inflammation
- Nutrients, hormones, and gene interactions
- The cancer industry: drug development and clinical trial design
- Cancer in the future: focus on diagnostics and immunotherapy.
- Notes:
- Includes bibliographical references and index.
- ISBN:
- 9780199211487
- 0199211485
- OCLC:
- 191751618
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.