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Translational research in genetics and genomics / Moyra Smith.

Holman Biotech Commons RB155 .S55 2008
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Levy Dental Medicine Library - Stacks RB155 .S55 2008
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Format:
Book
Author/Creator:
Smith, Moyra.
Language:
English
Subjects (All):
Medical genetics.
Genomics.
Genetics, Medical.
Genetic Diseases, Inborn.
Medical Subjects:
Genetics, Medical.
Genetic Diseases, Inborn.
Genomics.
Physical Description:
xiv, 220 pages : illustrations ; 25 cm
Place of Publication:
Oxford ; New York : Oxford University Press, 2008.
Contents:
Isolation of disease genes through genomics
Advances in genome analysis: discovery of structural variation and genomic dosage differences in health and disease
Significance of DNA sequence changes for diagnosis and therapy
Epigenetics
Complex diseases: molecular genetic contributions to elucidation of etiopathogenesis of late-onset neurodegenerative diseases
Advances in treatment of single gene disorders through translational science: treatment with small molecules (chaperones), and gene-based therapies
From gene discovery in genetic syndromes to identification of therapeutic agents
Impact of the environment on the genome
Molecular defects in cancer: application to therapy
Pharmacogenetics and pharmacogenomics
Phenomes, phenotypes, and clinical genetic services.
Notes:
Includes bibliographical references (pages 179-206) and index.
ISBN:
9780195313765
0195313763
OCLC:
171258242

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