Hair cell regeneration, repair, and protection / Richard J. Salvi, Arthur N. Popper, Richard R. Fay, editors.

Format:

Book

Contributor:

Salvi, Richard.

Popper, Arthur N.

Fay, Richard R.

Series:

Springer handbook of auditory research ; v. 33.

Springer handbook of auditory research ; v. 33

Language:

English

Subjects (All):

Hair cells.

Hair cells--Regeneration.

Hair Cells, Auditory.

Medical Subjects:

Hair Cells, Auditory.

Physical Description:

xii, 316 pages : illustrations ; 25 cm.

Place of Publication:

New York : Springer, [2008]

Summary:

The sensory hair cells in the inner ear and vestibular system convert mechanical stimuli, sound, and motion into neural activity that is responsible for the sensations of hearing, motion, and head position. In mammals, the loss of hair cells from acoustic overstimulation, ototoxic drugs, and aging is irreversible, leading to a permanent loss of function. However, it is now clear that hair cells in other vertebrates are capable of regenerating and recovering partial or complete function. Moreover, partially damaged hair cells can under-go self-repair or be protected from traumatic insults by external compounds.

Hair Cell Regeneration, Repair, and Protection provides a comprehensive survey of what is currently known about the regeneration, repair, and protection of sensory hair cells and subsequent recovery of function in the auditory and vestibular system. The aim is to provide graduate students, postdoctoral fellows, clinicians, and scientists in related disciplines with the biological bases of hair cells and with an understanding of the factors that contribute to their regeneration and repair.

Contents:

Overview: regeneration and repair / Richard J. Salvi

Morphological correlates of regeneration and repair in the inner ear / Jason R. Meyers and Jeffrey T. Corwin

Recovery of function in the avian auditory system after ototrauma / James C. Saunders and Richard J. Salvi

Functional recovery after hair cell regeneration in birds / Robert J. Dooling, Micheal L. Dent, Amanda M. Lauer, and Brenda M. Ryals

Hair cell regeneration: mechanisms guiding cellular proliferation and differentiation / Elizabeth C. Oesterle and Jennifer S. Stone

Protection and repair of inner ear sensory cells / Andrew Forge and Thomas R. Van De Water

Gene arrays, cell lines, stem cells, and sensory regeneration in mammalian ears / Marcelo N. Rivolta and Matthew C. Holley.

Notes:

Includes bibliographical references and index.

ISBN:

9780387733630

0387733639

OCLC:

181068596