Platelets in hematologic and cardiovascular disorders : a clinical handbook / edited by Paolo Gresele ... [and others].

Format:

Book

Contributor:

Gresele, Paolo, 1953-

Language:

English

Subjects (All):

Blood platelets.

Blood--Diseases.

Blood.

Cardiovascular system--Diseases.

Cardiovascular system.

Blood Platelets--pathology.

Blood Platelet Disorders--physiopathology.

Cardiovascular Diseases--physiopathology.

Hematologic Diseases--physiopathology.

Medical Subjects:

Blood Platelets--pathology.

Blood Platelet Disorders--physiopathology.

Cardiovascular Diseases--physiopathology.

Hematologic Diseases--physiopathology.

Physical Description:

xiii, 511 pages : illustrations (some color) ; 26 cm

Place of Publication:

Cambridge, UK ; New York : Cambridge University Press, 2008.

Summary:

A rapid increase in our understanding of the biology of platelets and their role in disease in recent years has been paralleled by increasing successes with established platelet-modifying therapies in many clinical conditions.

This new text focuses on the clinical role of platelets in a wide variety of haematologic, cardiovascular, and other disorders, providing a practical, clinically relevant handbook for all clinicians and researchers interested in platelets and their role in disease.

The book is organized in four sections: Platelet Physiology, Bleeding Disorders, Thrombotic Disorders and Antithrombotic Therapy. Chapters cover all the conventional and less conventional aspects of platelet involvement in disease, with an emphasis on recent clinical developments. Clear take-home messages have been included in each chapter to aid clinical practice.

With contributions from the leading experts across three continents, Platelets in Hematologic and Cardiovascular Disorders is an up-to-date, well-illustrated, practical resource for everyone involved in clinical practice with platelet disorders.

Contents:

1 The structure and production of blood platelets / Joseph E. Italiano, Jr. 1

2 Platelet immunology: structure, functions, and polymorphisms of membrane glycoproteins / Yasuo Ikeda, Yumiko Matsubara, Tetsuji Kamata 21

3 Mechanisms of platelet activation / Lawrence Brass, Timothy J. Stalker 37

4 Platelet priming / Paolo Gresele, Emanuela Falcinelli, Stefania Momi 53

5 Platelets and coagulation / Jose A. Lopez, Ian del Conde 79

6 Vessel wall-derived substances affecting platelets / Azad Raiesdana, Joseph Loscalzo 92

7 Platelet-leukocyte-endothelium cross talk / Kevin J. Croce, Masashi Sakuma, Daniel I. Simon 106

8 Laboratory investigation of platelets / Eduard Shantsila, Timothy Watson, Gregory Y.H. Lip 124

9 Clinical approach to the bleeding patient / Jos Vermylen, Kathelijne Peerlinck 147

10 Thrombocytopenia / James B. Bussel, Andrea Primiani 155

11 Reactive and clonal thrombocytosis / Ayalew Tefferi 186

12 Congenital disorders of platelet function / Marco Cattaneo 201

13 Acquired disorders of platelet function / Michael H. Kroll, Amy A. Hassan 225

14 Platelet transfusion therapy / Sherrill J. Slichter, Ronald G. Strauss 242

15 Clinical approach to the patient with thrombosis / Brian G. Choi, Valentin Fuster 261

16 Pathophysiology of arterial thrombosis / Juan Jose Badimon, Borja Ibanez, Gemma Vilahur 279

17 Platelets and atherosclerosis / Stephan Lindemann, Meinrad Gawaz 293

18 Platelets in other thrombotic conditions / David L. Green, Peter W. Marks, Simon Karpatkin 308

19 Platelets in respiratory disorders and inflammatory conditions / Paolo Gresele, Stefania Momi, Simon C. Pitchford, Clive P. Page 323

20 Platelet pharmacology / Dermot Cox 341

21 Antiplatelet therapy versus other antithrombotic strategies / Nicolai Mejevoi, Catalin Boiangiu, Marc Cohen 367

22 Laboratory monitoring of antiplatelet therapy / Paul Harrison, David Keeling 386

23 Antiplatelet therapies in cardiology / Pierluigi Tricoci, Robert A. Harrington 407

24 Antithrombotic therapy in cerebrovascular disease / James Castle, Gregory W. Albers 437

25 Antiplatelet treatment in peripheral arterial disease / Raymond Verhaeghe, Peter Verhamme 458

26 Antiplatelet treatment of venous thromboembolism / Menno V. Huisman, Jaapjan D. Snoep, Jouke T. Tamsma, Marcel M.C. Hovens 471.

Notes:

Includes bibliographical references and index.

ISBN:

9780521881159

0521881153

OCLC:

173201702

Online:

Contributor biographical information

Publisher description