Protein misfolding in neurodegenerative diseases : mechanisms and therapeutic strategies / edited by H. John Smith, Claire Simons, Robert D. E. Sewell.

Format:

Book

Contributor:

Smith, H. J., 1930-

Simons, Claire.

Sewell, Robert D. E.

Series:

CRC enzyme inhibitors series

Language:

English

Subjects (All):

Nervous system--Degeneration--Etiology.

Nervous system.

Nervous system--Degeneration--Treatment.

Nervous system--Degeneration--Pathophysiology.

Protein folding.

Neurodegenerative Diseases--etiology.

Protein Folding.

Neurodegenerative Diseases--physiopathology.

Neurodegenerative Diseases--therapy.

Nervous system--Degeneration.

Diseases--Causes and theories of causation.

Medical Subjects:

Neurodegenerative Diseases--etiology.

Protein Folding.

Neurodegenerative Diseases--physiopathology.

Neurodegenerative Diseases--therapy.

Physical Description:

xxiv, 565 pages, 4 unnumbered pages of plates : illustrations (partly color) ; 25 cm.

Place of Publication:

Boca Raton, FL : CRC Press, [2008]

Contents:

Protein folding and misfolding, relevance to disease, and biological function / Massimo Stefani

Alzheimer's disease / Charlotte E. Teunissen and Tischa J.M. van der Cammen

Improving cholinergic transmission

Cholinergic transmission and acetylcholine release enhancers / Pierre Francotte, Pascal de Tullio, and Bernard Pirotte

AChE and its inhibition / Jure Stojan

AChE inhibitors and their clinical assessment / Pierre Francotte, Pascal de Tullio, and Bernard Pirotte

Reduction in plaque formation

Secretase and APP processing / Christian Czech, Helmut Jacobsen, and Celine Adessi

Mechanism of plaque formation and Aβ aggregation inhibitors / Christian Czech, Helmut Jacobsen, and Celine Adessi

Nonsteroidal anti-inflammatory drugs / Bruno P. Imbimbo and Francesca Speroni

3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors / Dario Cattaneo

Aβ polymerization reduction / Harry LeVine III and Corrine E. Augelli-Szafran

Carbonic anhydrase activators as potential anti-Alzheimer's disease agents / Claudiu T. Supuran and Andrea Scozzafava

Detection and reduction of neurofibrillary lesions / Jeff Kuret

Protein misfolding in Alzheimer disease: pathogenic or protective? / Rudy J. Castellani ... [et al.]

Enhancement of brain retinoic acid levels / Ann B. Goodman ... [et al.]

Parkinson's disease: what is it? what causes it? and how can it be cured? / Tom Foltynie, Andrew W. Michell, and Roger A. Barker

Restoring dopamine levels / P. Nuno Palma .. [et al.]

Huntington's disease / Claire-Anne Gutekunst and Fran Norflus

Amyotrophic lateral sclerosis (motor neuron disease) / Teresa Sanelli ... [et al.]

Transmissible spongiform encephalopathies / Michael D. Geschwind and Giuseppe Legname

Overview / H. John Smith, Robert D.E. Sewell, and Claire Simons.

Notes:

Includes bibliographical references and index.

ISBN:

9780849373107

0849373107

OCLC:

130566692

Online:

Publisher description