Stroke recovery with cellular therapies / edited by Sean I. Savitz and Daniel M. Rosenbaum.

Format:

Book

Contributor:

Savitz, Sean I.

Rosenbaum, Daniel M.

Series:

Current clinical neurology

Language:

English

Subjects (All):

Cerebrovascular disease--Treatment.

Cerebrovascular disease.

Stem cells--Transplantation.

Stem cells.

Stem cells--Therapeutic use.

Stroke--therapy.

Stem Cell Transplantation--methods.

Brain Ischemia--therapy.

Intracranial Hemorrhages--therapy.

Stem Cell Transplantation--ethics.

Stromal Cells--transplantation.

Medical Subjects:

Stroke--therapy.

Stem Cell Transplantation--methods.

Brain Ischemia--therapy.

Intracranial Hemorrhages--therapy.

Stem Cell Transplantation--ethics.

Stromal Cells--transplantation.

Physical Description:

xviii, 166 pages, 7 unnumbered pages of plates : illustrations (partly color) ; 24 cm.

Place of Publication:

Totowa, N.J. : Humana Press, [2008]

Summary:

As the leading cause of adult disability, stroke poses substantial economic and psychological burdens to populations around the world. Against this dismal backdrop, several novel "neurorestorative" approaches are being investigated as adjunctive treatments to physiotherapy. Stroke Recovery with Cellular Therapies discusses the promising investigations around the world on cell-based therapies to enhance recovery from stroke. Throughout this groundbreaking text, chapters detail the potential benefits of various types of cells and approaches for ischemic and hemorrhagic stroke, and all studies rely upon traditional histological and functional outcomes. Among the topics detailed in this volume are transplanting immortalized neural stem cells, transplantation of bone marrow stromal cells, adipose-derived stem cells, endogenous neural stem cells in tissue remodeling, and an investigation into the ethics of stem cell research. This text provides an overview of the field, stimulates ideas for further research, and will help serve as a foundation for cell-based therapies to move forward as a viable approach for stroke recovery in the future.

Contents:

Safety and efficacy of transplanting immortalized neural stem cells in stroke patients / Maxim D. Hammer, Douglas Kondziolka and Lawrence R. Wechsler

Transplantation of bone marrow stromal cells for the treatment of stroke / Michael Chopp, Yi Li and Lihong Shen

Cord blood cells as a treatment for stroke / Alison E. Willing ... [et al.]

Adipose-derived stem cells as a potential therapy for stroke / Henry E. Rice and Kristine M. Safford

Novel imaging modalities to monitor implanted embryonic stem cells in stroke / Susanne Wegener and Mathias Hoehn

Cell transplantation for intracerebral hemorrhage / Kon Chu, Keun-Hwa Jung and Jae-Kyu Roh

Therapeutic strategies employing endogenous neural stem cells in tissue remodeling following ischemic injury: the promise, the peril and novel future applications / Mark F. Mehler

Ethics and stem cell research / Ruth Macklin

Special conditions in the design of clinical stroke trials for cell transplantation / Sean I. Savitz and Louis Caplan.

Notes:

Includes bibliographical references and index.

ISBN:

9781588297327

1588297322

OCLC:

166357976