Nanoparticles in biomedical imaging : emerging technologies and applications / edited by Jeff W.M. Bulte and Michel M.J. Modo.

Format:

Book

Contributor:

Bulte, Jeff W. M.

Modo, Michel Mathias Jeannot Joseph.

Series:

Fundamental biomedical technologies ; 102.

Fundamental biomedical technologies ; 102

Language:

English

Subjects (All):

Diagnostic Imaging.

Nanoparticles.

Imaging systems in medicine.

Medical Subjects:

Diagnostic Imaging.

Nanoparticles.

Physical Description:

xvii, 524 pages : illustrations.

Place of Publication:

New York, NY : Springer, [2008]

Summary:

Nanoparticles in Biomedical Imaging focuses on the use of nanoparticles as chemically engineered small entities that now have emerged as widely used diagnostic agents in biomedicine. The book is logically organized by the specific imaging modalities that are currently central in pre-clinical research and clinical routine, including magnetic resonance imaging, radionuclear imaging, ultrasound imaging, computed tomography, and optical imaging. This comprehensive title provides an expert opinion on the latest developments in biomedical imaging using nanoparticles.

Key topics: Use of superparamagnetic iron oxide nanoparticles in magnetic resonance imaging, Radiolabeled liposomes and their applications in nuclear medicine, Ultrasound bubbles as acoustically reflective medium, Exploiting iodinated nanoparticles with computed tomography, Quantum dots: the bright future of semiconducting optical agents. Nanoparticles in Biomedical Imaging will serve as a useful and valuable resource on the fundamental science of diagnostic nanoparticles in their interactions with biological targets, providing a platform technology for clinical implementation and improved detection of disease.

Contents:

1 Introduction: The Emergence of Nanoparticles as Imaging Platform in Biomedicine / Jeff. W.M. Bulte, Michel M.J. Modo 1

Part 1 (Para)magnetic Nanoparticles: Applications in Magnetic Resonance Imaging

2 MR Lymphangiography Using Nano-Sized Paramagnetic Contrast Agents with Dendrimer Cores / Hisataka Kobayashi 9

3 Use of USPIOs for Clinical Lymph Node Imaging / Jelle O. Barentsz, Paris P. Tekkis 25

4 Use of SPIOs for Clinical Liver Imaging / Akihiro Tanimoto 41

5 The Emerging Role of USPIOs for MR Imaging of Atherosclerosis / M.E. Kooi, S. Heeneman, M.J.A.P. Daemen, J.M.A. van Engelshoven, K.B.J.M. Cleutjens 63

6 (Super)paramagnetic Nanoparticles: Applications in Noninvasive MR Imaging of Stem Cell Transfer / Glenn A. Walter, Swadeshmukul Santra, Bijoy Thattaliyath, Samuel C. Grant 91

7 Micron-Sized Iron Oxide Particles (MPIOs) for Cellular Imaging: More Bang for the Buck / Erik M. Shapiro, Alan P. Koretsky 141

8 Molecular MR Imaging with Paramagnetic Perfluorocarbon Nanoparticles / Patrick M. Winter, Shelton D. Caruthers, Anne H. Schmieder, Anne M. Neubauer, Gregory M. Lanza, Samuel A. Wickline 163

9 Magnetic Nanosensors for Probing Molecular Interactions / J. Manuel Perez, Charalambos Kaittanis 183

10 Magnetoptical Probes / Eyk Schellenberger 199

Part 2 Radiolabeled Nanoparticles: Applications in Nuclear Medicine

11 Use of Radiolabeled Liposomes for Tumor Imaging / Tamer Elbayoumi, Vladimir Torchilin 211

12 Use of Radiolabeled Liposomes for Imaging of Infection and Inflammation / Peter Laverman, Gert Storm, Otto C. Boerman 237

13 Sulphur Colloid for Imaging Lymph Nodes and Bone Marrow / Frederick L. Moffat, Jr., Seza A. Gulec 253

Part 3 Acoustically Reflective Nanoparticles: Application in Ultrasound Imaging

14 Use of Ultrasound Bubbles in Lymph Node Imaging / Erik R. Wisner, Susannah H. Bloch 289

15 Use of Ultrasound Microbubbles for Vascular Imaging / Yuko Kono, Thilo Holscher, Robert F Mattrey 311

16 Targeted Microbubbles: Ultrasound Contrast Agents for Molecular Imaging / Alexander L. Klibanov 327

17 Use of Acoustically Active Contrast Agents in Imaging of Inflammation and Atherosclerosis / Patrick H. Kee, David D. McPherson 343

Part 4 Iodinated Nanoparticles: Applications in Computed Tomography

18 Iodinated Liposomes as Contrast Agents / Andreas Sachse 371

Part 5 Quantum Dots: Applications in Optical Imaging

19 Quantum Dots and Targeted Nanoparticle Probes for In Vivo Tumor Imaging / Matthew N. Rhyner, Andrew M. Smith, Xiaohu Gao, Hui Mao, Lily Yang, Shuming Nie 413

20 Investigating the Dynamics of Cellular Processes at the Single Molecule Level with Semiconductor Quantum Dots / Maxime Dahan 427

21 Targeting Vascular Epitopes Using Quantum Dots / Dardo E. Ferrara, Charles Glaus, W. Robert Taylor 443

22 Quantum Dots for Cancer Imaging / Swadeshmukul Santra, Debamitra Dutta 463

23 Bimodal Liposomes and Paramagnetic QD-Micelles for Multimodality Molecular Imaging of Tumor Angiogenesis / Willem J.M. Mulder, Gustav J. Strijkers, Rolf Koole, Celso De Mello Donega, Gert Storm, Arjan W. Griffioen, Klaas Nicolay 487.

Notes:

Includes bibliographical references and index.

ISBN:

9780387720265

038772026X

9780387720272

0387720278

OCLC:

173498949

Online:

Publisher description