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Interaction between neurons and glia in aging and disease / edited by João O. Malva ; co-editors, Ana C. Rego, Rodrigo A. Cunha, and Catarina R. Oliveira.

Holman Biotech Commons RC346 .I54 2007 1 v. + DVD
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Format:
Book
Contributor:
Malva, João O.
Language:
English
Subjects (All):
Geriatric neurology.
Astrocytes.
Neurons.
Aging--pathology.
Nerve Degeneration--pathology.
Neurodegenerative Diseases.
Neuroglia--pathology.
Neurons--pathology.
Medical Subjects:
Aging--pathology.
Nerve Degeneration--pathology.
Neurodegenerative Diseases.
Neuroglia--pathology.
Neurons--pathology.
Physical Description:
ix, 521 pages : illustrations (some color) ; 25 cm + 1 DVD (sound, color ; 4 3/4 in.)
Place of Publication:
New York, NY : Springer, [2007]
System Details:
Accompanying DVD is playable on NTSC and PAL video players, as well as most computer-based media players.
Summary:
Interaction Between Neurons and Glia in Aging and Disease is an indispensable source of reference reviews and concise overviews of the functional cross-talk between neurons and glial cells.This key title specifically focuses on microglia and inflammation in the aging brain and in neurological disorders. The subject material covered by the book is a crucial competitive area with critical implications for human health and will be of key interest to the scientific community.
Interaction Between Neurons and Glia in Aging and Disease is broken into three main sections to help guide the reader from the basic functional cross-talk between neuron and glia to brain pathology. Neuroimmunity and neuroinflammation, Signaling and inflammation in aging, Neurodegeneration and inflammation in age related diseases. This unique volume will be invaluable not only to those interested in neuroscience, but also cell biology, molecular biology, biochemistry, and pharmaceutical sciences.
Contents:
Section 1 Neuroimmunity and neuroinflammation / Joao O. Malva, Catarina R. Oliveira 1
Chapter 1 Inflammation and Neuronal Susceptibility to Excitotoxic Cell Death / Liliana Bernardino, Joao O. Malva 3
Chapter 2 Microglial Cell Population Expansion Following Acute Neural Injury / M. Wirenfeldt, L. Dissing-Olesen, A.A. Babcock, R. Ladeby, M.B. Jensen, T. Owens, B. Finsen 37
Chapter 3 Opposite Modulation of Peripheral Inflammation and Neuroinflammation by Adenosine A[subscript 2A] Receptors / Rodrigo A. Cunha, Jiang-Fan Chen, Michail V. Sitkovsky 53
Chapter 4 Subventricular Zone Cells as a Tool for Brain Repair / Fabienne Agasse, Liliana Bernardino, Joao O. Malva 81
Section 2 Signaling and inflammation in aging / Rodrigo A. Cunha 109
Chapter 5 Neuron-Glia Interaction in Homeostasis of the Neurotransmitters Glutamate and GABA / Arne Schousboe, Helle S. Waagepetersen 111
Chapter 6 The Impact of an Imbalance Between Proinflammatory and Anti-inflammatory Influences on Synaptic Function in the Aged Brain / Marina Lynch 121
Chapter 7 Neurotrophin Signaling and Cell Survival / Bruno J. Manadas, Carlos V. Melo, Joao R. Gomes, Carlos B. Duarte 137
Chapter 8 GDNF: a Key Player in Neuron-Glia Crosstalk and Survival of Nigrostriatal Dopaminergic Neurons / Emilia P. Duarte, Ana Saavedra, Graca Baltazar 173
Chapter 9 Molecular Pathways of Mitochondrial Dysfunction in Neurodegeneration: the Paradigms of Parkinson's and Huntington's Diseases / Ana Cristina Rego, Sandra Morais Cardoso, Catarina R. Oliveira 193
Chapter 10 Zinc Homeostasis and Brain Injury / Stefano Sensi, Erica Rockabrand, Israel Sekler 221
Chapter 11 Aging and Cognitive Decline: Neuroprotective Strategies / Frederico Simoes do Couto, Alexandre de Mendonca 245
Section 3 Neurodegeneration and inflammation in age related diseases / Ana Cristina Rego, Catarina R. Oliveira 269
Chapter 12 Inflammation and Apoptotic Pathways in the Peripheral Nervous System Related to Protein Misfolding / Maria Joao Saraiva 271
Chapter 13 Neuroinflammation and Excitotoxicity in Neurobiology of HIV-1 Infection and AIDS: Targets for Neuroprotection / Marcus Kaul, Stuart A. Lipton 281
Chapter 14 Neuroinflammation and Mitochondrial Dysfunction in Alzheimer's and Prion's Diseases / Paula Agostinho, Catarina R. Oliveira 309
Chapter 15 Metal Ions and Alzheimer's Disease / Paul A. Adlard, Ashley I. Bush 333
Chapter 16 Epilepsy, Brain Injury and Cell Death / Gunther Sperk, Meinrad Drexel, Ramon Tasan, Anna Wieselthaler 363
Chapter 17 Glia and Hippocampal Neurogenesis in the Normal, Aged and Epileptic Brain / William P. Gray, Alexandra Laskowski 375
Chapter 18 Polyglutamine Expansion Diseases - the Case of Machado-Joseph Disease / Sandra Macedo-Ribeiro, Luis Pereira de Almeida, Ana Luisa Carvalho, Ana Cristina Rego 391
Chapter 19 Remyelination of the Central Nervous System / Charlotte C. Bruce, Robin J. M. Franklin, Joao B. Relvas 427
Chapter 20 Adult Neurogenesis in Neurodegenerative Diseases / Tomas Deierborg, Jia-Yi Li, Patrik Brundin 445
Chapter 21 ATP Receptors in the Pain Signaling: Glial Contribution in Neuropathic Pain / Kazuhide Inoue 461
Chapter 22 Diabetic Retinopathy, Inflammation, and Proteasome / Antonio F. Ambrosio, Paulo Pereira, Jose Cunha-Vaz 475
Chapter 23 Rejuvenating Neurons and Glia with Microbial Enzymes / Aubrey D.N.J. de Grey 503.
Notes:
Includes bibliographical references and index.
ISBN:
0387708294
9780387708294
OCLC:
85689802

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