Dietary supplements and health / [editors: Gregory Bock and Jamie Goode].

Format:

Book

Contributor:

Bock, Gregory.

Goode, Jamie.

Novartis Foundation.

Series:

Novartis Foundation symposium ; no. 282.

Novartis Foundation symposium ; no. 282

Language:

English

Subjects (All):

Dietary supplements--Evaluation--Congresses.

Dietary supplements.

Dietary supplements--Health aspects--Congresses.

Dietary supplements--Safety measures--Congresses.

Dietary Supplements.

Industrial safety.

Evaluation.

Medical Subjects:

Dietary Supplements.

Genre:

Conference papers and proceedings.

Physical Description:

viii, 228 pages : illustrations ; 24 cm.

Place of Publication:

Chichester : John Wiley, 2007.

Summary:

Dietary supplements can contain a wide variety of ingredients, either singly or in combination, including nutrients, botanicals and 'bioactive components' commonly found in foods. They are marketed and used by consumers for a range of reasons: to enhance "well-being", as traditional medicines, for health promotion or disease risk reduction, and as alternatives or complements to conventional drug therapies.

On a global basis, the dietary supplement industry has enjoyed rapid growth, becoming a multi-billion dollar enterprise over the last 10 years. This growth has been associated with significant changes in both the types of products available and the reasons for using these products. In many cases, these changes have occurred without the benefit of a sound scientific basis for evaluating the safety and efficacy of these products under the new conditions of use. Frequently the same limited scientific evidence is used, even though current product composition, user populations, purported beneficial effects, and conditions of use may differ significantly from the available evidence or historical usage.

This book presents systematic examinations of the scientific data that are available and/or needed to substantiate and evaluate the safety and efficacy of dietary supplements. A series of case studies that are illustrative of the types of scientific challenges that have been encountered in substantiating safety and efficacy for various product types are employed to point out some of the successes but also frustrations that have occurred in recent years. Discussions among presenters and participants identify the lessons learned from these experiences and formulate ideas for improved approaches to identifying research needs and for enhancing the quality and relevance of the scientific evidence available for policy decisions. Dietary Supplements and Health constitutes a useful resource for nutritionists, biochemists, public health researchers and anyone interested in herbal alternative medicines.

Contents:

Barry Halliwell Chair's introduction 1

/ Alan R. Boobis Risk assessment of dietary supplements 3

/ Robert M. Russell Setting dietary intake levels: problems and pitfalls 29

/ Peter J. Aggett Criteria for substantiating claims 46

/ Elizabeth A. Yetley Science in the regulatory setting: a challenging but incompatible mix? 59

/ Roland Stocker Vitamin E 77

/ Barry Halliwell Flavonoids: a re-run of the carotenoids story? 93

/ John M. Scott Reduced folate status is common and increases disease risk. It can be corrected by daily ingestion of supplements or fortification 105

/ Kevin D. Cashman Calcium and vitamin D 123

/ Jan Alexander Selenium 143

/ Edzard Ernst Herbal medicines: balancing benefits and risks 154

/ E. L. Yong, S. P. Wong, P. Shen, Y. H. Gong, J. Li, Y. Hong Standardization and evaluation of botanical mixtures: lessons from a traditional (Chinese herb, Epimedium, with oestrogenic properties 173

/ Hildegard Przyrembel Communication between science and management 192

/ Paul M. Coates Dietary supplements and health: the research agenda 202.

Notes:

Contain articles from Symposium on Dietary supplements and health, held at the Novartis Foundation, London, 9-11 May 2006.

Includes bibliographical references and indexes.

ISBN:

9780470034279

0470034270

OCLC:

76851438