The way of synthesis : evolution of design and methods for natural products / Tomáš Hudlický and Josephine W. Reed.

Format:

Book

Author/Creator:

Hudlicky, Tomas.

Contributor:

Reed, Josephine W., 1949-

Language:

English

Subjects (All):

Biosynthesis.

Natural products.

Physical Description:

xv, 1004 pages : illustrations ; 25 cm

Place of Publication:

Weinheim : Wiley-VCH ; Chichester : John Wiley [distributor], [2007]

Summary:

At the center of organic chemistry is the effective synthesis of natural products and other compounds of importance to society such as pharmaceuticals and agrochemicals. This textbook presents both strategy of design as well as tactics of execution in a comparative view of several designs for the same targets. An overview of the history and evolution of synthesis is provided followed by the discussion of achievements in total synthesis of natural products spanning almost 60 years. The sections on comparative design cover classics in terpenes and alkaloid synthesis, with an additional part on miscellaneous targets such as maytansine, palytoxin, brevetoxin B and indinavir. An outlook of future perspectives is provided with the discussion of various factors influencing organic synthesis. With its attractive two-color layout highlighting key stategies and tactics, this book is useful to synthetic chemists at all levels: lecturers and students as well as professionals in industry.

Contents:

Introduction

Strategy and tactics

Comparative design: classics in terpene synthesis

Comparative design: classics in alkaloid synthesis

Miscellaneous compounds

Outlook.

Notes:

Includes bibliographical references and index.

ISBN:

9783527320776

3527320776

352731444X

9783527314447

OCLC:

72868951