Cell culture and upstream processing / edited by Michael Butler.

Format:

Book

Contributor:

Butler, M. (Michael), 1947-

Louis A. Duhring Fund.

Language:

English

Subjects (All):

Cell culture--Congresses.

Cell culture.

Biochemical engineering--Congresses.

Biochemical engineering.

Biotechnology--Congresses.

Biotechnology.

Cell Culture Techniques--methods.

Genetic Engineering--methods.

Medical Subjects:

Cell Culture Techniques--methods.

Genetic Engineering--methods.

Genre:

Conference papers and proceedings.

Physical Description:

xiv, 187 pages : illustrations ; 25 cm

Place of Publication:

New York ; Abingdon [England] : Taylor & Francis, [2007]

Summary:

Each chapter in Cell Culture and Upstream Processing is taken from presentations at the highly acclaimed IBC conferences as well as meetings of the European Society for Animal Cell Technology (ESACT) and Protein Expression in Animal Cells (PEACe). Chapters describe how to improve yield and optimize the cell culture production process for biopharmaceuticals, by focusing on safety, quality, economics and operability and productivity issues.

Cell Culture and Upstream Processing will appeal to a wide scientific audience, both scientific practitioners of animal cell technology as well as graduate or upper-level undergraduate students taking courses in biochemical engineering or biotechnology.

Contents:

Cell line development and culture strategies : future prospects to improve yields / Michael Butler

Use of DNA insulator elements and scaffold/matrix-attached regions for enhanced recombinant protein expression / Helen Kim

Targeted gene insertion to enhance protein production from cell lines / Trevor N. Collingwood and Fyodor D. Urnov

Recombinant IgG production from myeloma and Chinese hamster ovary cells / Ray Field

Cell culture media development : customization of animal origin-free components and supplements / Stephen Gorfien

Post-translational modification of recombinant proteins / Roy Jeffries

Metabolic engineering to control glycosylation / Amy Shen ... [et al.]

An alternative approach : humanization of N-glycosylation pathways in yeast / Stefan Wildt and Thomas Potgieter

Perfusion or fed-batch? : a matter of perspective / Marco Cacciuttolo.

Notes:

"From presentations at the ... IBC conferences as well as meetings of the European Society for Animal Cell Technology (ESACT) and Protein Expression in Animal Cells (PEACe)."

Includes bibliographical references and index.

Local Notes:

Acquired for the Penn Libraries with assistance from the Louis A. Duhring Fund.

ISBN:

9780415399692

0415399696

OCLC:

82473211