Bacteriocins : ecology and evolution / M. A. Riley, M.A. Chavan (eds.).

Format:

Book

Contributor:

Riley, M. A. (Margaret A.)

Chavan, M. A. (Milind A.)

Language:

English

Subjects (All):

Bacteriocins.

Gram-positive bacteria.

Gram-negative bacteria.

Gram-Positive Bacteria.

Gram-Negative Bacteria.

Medical Subjects:

Bacteriocins.

Gram-Positive Bacteria.

Gram-Negative Bacteria.

Physical Description:

x, 150 pages : illustrations (partly color) ; 24 cm

Place of Publication:

Berlin : Springer, 2007.

Summary:

Microbes produce an extraordinary array of defense system. These include bacteriocins, a class of antimicrobial molecules with narrow killing spectra, produced by bacteria. The book describes the diversity and ecological role of bacteriocins of Gram-positive and Gram-negative bacteria, presenting a new classification scheme for the former and a state-of-the-art look at the role of bacteriocins in bacterial communication. It discusses the molecular evolution of colicins and colicin-like bacteriocins, and provides a contemporary overview of archaeocins bacteriocin-like antimicrobials produced by archaebacteria. Furthermore, various modeling (in silico) studies elucidate the role of bacteriocins in microbial community dynamics and fitness, delving into rock-paper-scissors competition and the counter-intuitive survival of the weakest. The book makes compelling reading for a multi-faceted scientific audience, including those working in the fields of biodiversity and biotechnology, notably in the human and animal health domain.

Contents:

2 The Diversity of Bacteriocins in Gram-Negative Bacteria / David M. Gordon, Elizabeth Oliver, Jane Littlefield-Wyer 5

2.2 The Frequency of Bacteriocin Production 7

2.2.1 Colicins 7

2.2.2 Microcins 8

2.3 Bacteriocin Diversity 9

2.3.1 Colicins 9

2.3.2 Microcins 10

2.4 Multiple Bacteriocin Production 11

3 Molecular Evolution of Bacteriocins in Gram-Negative Bacteria / Milind A. Chavan, Margaret A. Riley 19

3.2 Bacteriocins of Gram-Negative Bacteria 20

3.3 Colicins and Colicin-like Bacteriocins 21

3.3.1 Colicin Gene Organization 21

3.3.2 Functional Domains in Colicin and CLB Proteins 23

3.4 Models of Colicin Evolution 25

3.4.1 Diversifying Selection 25

3.4.2 Diversifying Recombination 27

3.4.3 Evolution of Colicin-like Bacteriocins 27

3.5 Evolution of Colicin Killing Domains 29

3.6 Evolution of the Translocation and Receptor-Binding Domains 36

3.7 Evolution of Colicin Regulatory Sequences 37

3.8 Colicin D: A Possible Intermediate Between Pyocins and Colicins 38

4 The Diversity of Bacteriocins in Gram-Positive Bacteria / Nicholas C.K. Heng, Philip A. Wescombe, Jeremy P. Burton, Ralph W. Jack, John R. Tagg 45

4.1.1 Bacteriocins: A Historical Perspective 45

4.1.2 Bacteriocins of Gram-Positive Bacteria 46

4.1.3 Why Produce Bacteriocins? 47

4.1.4 Detection of Bacteriocins of Gram-Positive Bacteria 48

4.1.5 Nomenclature of Bacteriocins of Gram-Positive Bacteria 49

4.1.6 Classification of Bacteriocins of Gram-Positive Bacteria 50

4.2 Class I: The Lanthionine-Containing (Lantibiotic) Bacteriocins 53

4.2.1 Type AI Lantibiotics 53

4.2.2 Type AII Lantibiotics 58

4.2.3 Type B (Globular) Lantibiotics 61

4.2.4 Type C (Multi-Component) Lantibiotics 62

4.3 Class II: The Unmodified Peptide Bacteriocins 64

4.3.1 Type IIa: The Pediocin-like Peptides 64

4.3.2 Type IIb: Multi-Component Bacteriocins 66

4.3.3 Type IIc: Miscellaneous Unmodified Bacteriocins 61

4.4 Class III: The Large (> 10 kDa) Bacteriocins 74

4.4.1 Type IIIa: The Bacteriolysins (Bacteriolytic Enzymes) 74

4.4.2 Type IIIb: The Non-Lytic Bacteriocins 78

4.5 Class IV: The Cyclic Bacteriocins 79

4.5.1 Enterocin AS-48 81

4.5.2 Gassericin A and Reutericin 6 82

4.5.3 Uberolysin 82

5 Peptide and Protein Antibiotics from the Domain Archaea: Halocins and Sulfolobicins / Richard F. Shand, Kathryn J. Leyva 93

5.2 Halocins 94

5.2.1 The Ubiquity of Halocin Production 94

5.2.2 The Role of Halocins in the Environment and the Inability to Detect Halocin Activity in Hypersaline Crystallizer Ponds 98

5.2.3 Activity Spectra 99

5.2.4 Common Features of Halocins 101

5.2.5 Microhalocins ([less than or equal] 10 kDa) 102

5.2.6 Protein Halocins (> 10 kDa) 104

5.3 Biotechnology of Halocins 106

5.4 Sulfolobicins 106

6 The Ecological and Evolutionary Dynamics of Model Bacteriocin Communities / Benjamin Kerr 111

6.2 Dynamics in Two-Strain Communities: Getting over the Hump 113

6.3 Dynamics in Three-Strain Communities: Playing Rock-Paper-Scissors 119

6.4 Evolution in Three-Strain Communities: Survival of the Weakest 125

6.5 Dynamics with many Strains: Universal Chemical Warfare 128

Appendix Sensitivity is an ESS in the Well-Mixed RPS Game 131

7 Bacteriocins' Role in Bacterial Communication / Osnat Gillor 135

7.2 Bacteriocin-Mediated Intercellular Communication 137

7.2.1 Autoregulation of Class I Bacteriocins 138

7.2.2 Quorum Sensing Regulation of Class II Bacteriocins 138

7.3 Bacteriocin-Coordinated Multicellular Communication 139

7.3.1 Oral Biofilms 140

7.3.2 Gastrointestinal Biofilms 141.

Notes:

Includes bibliographical references and index.

ISBN:

3540366032

9783540366034

OCLC:

75253357