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Viral pathogenesis and immunity / Neal Nathanson ; co-authors, Rafi Ahmed ... [and others].

Holman Biotech Commons QR201.V55 V533 2007
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Levy Dental Medicine Library - Stacks QR201.V55 V533 2007
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Format:
Book
Contributor:
Nathanson, Neal.
Ahmed, Rafi.
Language:
English
Subjects (All):
Virus diseases--Pathogenesis.
Virus diseases.
Virus diseases--Immunological aspects.
Host-virus relationships.
Viruses--pathogenicity.
Virus Diseases--etiology.
Virus Diseases--immunology.
Medical Subjects:
Viruses--pathogenicity.
Virus Diseases--etiology.
Virus Diseases--immunology.
Physical Description:
xi, 266 pages : color illustrations, color maps ; 30 cm
Edition:
Second edition.
Place of Publication:
London ; Burlington, Mass. : Elsevier Academic Press, [2007]
Summary:
Based on the highly successful reference work Viral Pathogenesis, this concise version can be used as an introductory text or for self-education by medical students and biologists alike. This latest edition provides a completely revised overview of the subject with new chapters on innate immunity, emerging viral diseases, and antiviral therapy. Information is presented in a format that is easy to understand with copious examples that illustrate the experimental basis of important generalizations. Used by the lead author in his graduate classes, it sets forth essential principles and discusses the role of immunity and other host defenses. The book explains how viral pathogenesis can be used for the rational development of treatment and prevention of viral diseases. The only introductory text devoted exclusively to this topic. Focuses specifically on viral pathogenesis unlike other texts where only a few chapters are devoted to the topic, A 20% expansion over the first edition, Now in four color throughout!
Contents:
List of Co-authors vii
Part 1 Essentials of Viral Pathogenesis 1
1 Historical Roots / Neal Nathanson, Frederick A. Murphy 3
2 The Sequential Steps in Viral Infection / Neal Nathanson, Frederick A. Murphy 14
3 Cellular Receptors and Viral Tropism / Neal Nathanson, Kathryn V. Holmes 27
4 Virus-Cell Interactions / Neal Nathanson, Diane E. Griffin 41
Part II Host Responses to Viral Infection 57
5 Innate Immunity / Neal Nathanson, Christine A. Biron 59
6 Immune Responses to Viral Infection / Neal Nathanson, Rafi Ahmed 72
7 Virus-Induced Immunopathology / Neal Nathanson, Rafi Ahmed 88
8 Virus-Induced Immunosuppression / Neal Nathanson, Diane E. Griffin 99
Part III Virus-Host Interactions 111
9 Viral Virulence / Neal Nathanson, Francisco Gonzalez-Scarano 113
10 Viral Persistence / Neal Nathanson, Francisco Gonzalez-Scarano 130
11 Viral Oncogenesis: Retroviruses / Neal Nathanson, Harriet L. Robinson 146
12 Viral Oncogenesis: DNA Viruses / Neal Nathanson, Erle S. Robertson 158
13 Host Susceptibility to Viral Diseases / Neal Nathanson, Margo A. Brinton 174
14 HIV, SIV and the Pathogenesis of AIDS / Neal Nathanson, Julie Overbaugh 185
Part IV Ecology and Control of Viral Infections 201
15 Emergirig Viral Diseases / Neal Nathanson, Frederick A. Murphy 203
16 Antiviral Therapy / Neal Nathanson, Douglas D. Richman 221
17 Viral Vaccines / Neal Nathanson, Harriet L. Robinson 234.
Notes:
Includes bibliographical references and index.
ISBN:
0123694647
9780123694645
OCLC:
123373755

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