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Bone marrow and stem cell transplantation / edited by Meral Beksac.
Table of contents only Available online
View onlineHolman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
Available
LIBRA RD123.5 .B66 2007
Available from offsite location
- Format:
- Book
- Series:
- Methods in molecular medicine 1064-3745 ; 134.
- Methods in molecular medicine, 1064-3745 ; 134
- Language:
- English
- Subjects (All):
- Bone marrow--Transplantation.
- Bone marrow.
- Bone Marrow Transplantation--immunology.
- Bone Marrow Transplantation--methods.
- HLA Antigens--immunology.
- Hematopoietic Stem Cell Transplantation--methods.
- Hematopoietic Stem Cells--immunology.
- Histocompatibility Testing.
- Medical Subjects:
- Bone Marrow Transplantation--immunology.
- Bone Marrow Transplantation--methods.
- HLA Antigens--immunology.
- Hematopoietic Stem Cell Transplantation--methods.
- Hematopoietic Stem Cells--immunology.
- Histocompatibility Testing.
- Physical Description:
- x, 234 pages : illustrations (some color) ; 24 cm.
- Place of Publication:
- Totowa, N.J. : Humana Press, [2007]
- Summary:
- This volume is a compendium of cutting-edge molecular methods for the successful transplantation of hematopoietic stem cells. The availability of genetic profiles for committed and uncommitted stem cells combined with the determination of molecular steps involved in hematopoietic stem cell activation and self-renewal hold tremendous promise for future success in the clinic. Currently, stem cells can be quantified and sorted successfully, but transduction, labeling, and in vivo tracking of stem cells are difficult techniques with traditionally low efficiency levels. The contributors to this volume describe promising tools for stem cell transplant research models, such as in vivo bioluminescence imaging.
- Topics included in this volume are molecular profiling of hematopoietic stell cells, methods for imaging cell fates in hematopoiesis, PCR-SSP typing of HLA Class I and Class II alleles, sequence-based HLA typing, and typing minor HLA antigens. Also discussed in this volume are the roles of natural killer cells and killer inhibitor receptor polymorphisms, polymorphisms within epithelial receptors, molecular methods used for the detection of autologous graft contamination in lymphoid disorders, and the application of proteomics to posttransplantation follow-up.
- With the recent trend moving from gene expression to the protein expression profiles, the application of proteomics to the posttransplant follow-up of patients is becoming routine. As a result, this volume will become an invaluable source for biochemists, molecular biologists, and clinicians. Features: Discussion of HLA typing, PCR-SSP typing, HLA antigens, Chapters written by world-renown leaders in the field.
- Contents:
- 1 Molecular Profiling of Hematopoietic Stem Cells / Teresa V. Bowman, Akil A. Merchant, Margaret A. Goodell 7
- 2 Methods for Imaging Cell Fates in Hematopoiesis / Jennifer Duda, Mobin Karimi, Robert S. Negrin, Christopher H. Contag 17
- 3 An Overview of HLA Typing for Hematopoietic Stem Cell Transplantation / Ann-Margaret Little 35
- 4 Sequence-Specific Primed PCR (PCR-SSP) Typing of HLA Class I and Class II Alleles / Klara Dalva, Meral Beksac 51
- 5 HLA Typing with Sequence-Specific Oligonucleotide Primed PCR (PCR-SSO) and Use of the Luminex Technology / Klara Dalva, Meral Beksac 61
- 6 Sequencing-Based Typing of HLA / Berthold Hoppe, Abdulgabar Salama 71
- 7 Molecular Typing Methods for Minor Histocompatibility Antigens / Eric Spierings, Els Goulmy 81
- 8 Non-HLA Polymorphisms in Stem Cell Transplantation / Pete G. Middleton 97
- 9 Polymorphisms Within Epithelial Receptors: NOD2/CARD15 / Julia Brenmoehl, Ernst Holler, Gerhard Rogler 115
- 10 Role of Natural Killer Cells and Killer Immunoglobulin-like Receptor Polymorphisms: Association of HLA and KIRs / M. Tevfik Dorak 123
- 11 Identification of Bone Marrow Derived Nonhematopoietic Cells by Double Labeling with Immunohistochemistry and In Situ Hybridization / Isinsu Kuzu, Meral Beksac 145
- 12 Molecular Methods Used for Detection of Minimal Residual Disease Following Hematopoietic Stem Cell Transplantation in Myeloid Disorders / Ahmet H. Elmaagacli 161
- 13 Molecular Methods Used for the Detection of Autologous Graft Contamination in Lymphoid Disorders / Paolo Corradini, Matteo G. Carrabba, Lucia Farina 179
- 14 Detection of Impending Graft Rejection and Relapse by Lineage-Specific Chimerism Analysis / Thomas Lion 197
- 15 Application of Proteomics to Posttransplantation Follow-Up / Eva M. Weissinger, Harald Mischak 217.
- Notes:
- Includes bibliographical references and index.
- ISBN:
- 1588295958
- 9781588295958
- 1597452238
- 9781597452236
- OCLC:
- 68705618
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