Microarray technology and cancer gene profiling / edited by Simone Mocellin.

Format:

Book

Contributor:

Mocellin, Simone.

Series:

Advances in experimental medicine and biology ; v. 593.

Advances in experimental medicine and biology ; v. 593

Language:

English

Subjects (All):

Oncogenes.

DNA microarrays.

Neoplasms--genetics.

Gene Expression Profiling--methods.

Microarray Analysis--methods.

Medical Subjects:

Neoplasms--genetics.

Gene Expression Profiling--methods.

Microarray Analysis--methods.

Physical Description:

xviii, 159 pages : illustrations (some color) ; 26 cm.

Place of Publication:

New York, N.Y. : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience/Eurekah.com, [2007]

Summary:

Given the revolutionary implications that the use of this technology might have in the clinical management of cancer patients, the principles of DNA array-based tumor gene profiling must be clearly understood for the data to be correctly interpreted and appreciated. This book, written by leading experts, discusses the technical features characterizing the powerful laboratory tool of microarray technology, and reviews applications in the field of oncology.

Contents:

Manufacturing of microarrays

Technological platforms for microarray gene expression profiling

Principles of gene microarray data analysis

Gaining weights ... and feeling good about it!

Complementary techniques

Microarrays for cancer diagnosis and classification

Gene profiling for the prediction of tumor response to treatment: the case of immunotherapy

Identification of molecular determinants of tumor sensitivity and resistance to anticancer drugs

SNP and mutation analysis

Cancer development and progression

Gene expression profiling in malignant lymphomas

Tumor immunology.

Notes:

Includes bibliographical references and index.

ISBN:

9780387399775

0387399771

OCLC:

70921484