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Developing biomarker-based tools for cancer screening, diagnosis, and treatment : the state of the science, evaluation, implementation, and economics : workshop summary / Margie Patlak and Sharyl Nass, rapporteurs ; National Cancer Policy Forum.
Levy Dental Medicine Library - Stacks RC270.3.T84 P38 2006
Available
- Format:
- Book
- Author/Creator:
- Patlak, Margie.
- Language:
- English
- Subjects (All):
- Tumor markers--Congresses.
- Tumor markers.
- Neoplasms--prevention & control.
- Mass Screening--methods.
- Biomarkers, Tumor--analysis.
- Medical Subjects:
- Neoplasms--prevention & control.
- Mass Screening--methods.
- Biomarkers, Tumor--analysis.
- Genre:
- Conference papers and proceedings.
- Physical Description:
- x, 102 pages : illustrations ; 23 cm
- Place of Publication:
- Washington, D.C. : National Academies Press, [2006]
- Contents:
- Overview of Technologies Used to Discover Cancer Biomarkers 3
- Genomics, Proteomics, and Metabolomics 3
- Molecular Imaging 9
- Meeting the Technical Challenges of Biomarker Validation and Qualification 11
- Coordinating the Development of Biomarkers and Targeted Therapies 20
- Therapeutics Industry Perspective 21
- Diagnostics Industry Perspective 24
- NCI Perspective 26
- Clinical Investigator Perspective 28
- Biomarker Development and Regulatory Oversight 29
- FDA Critical Path Initiative 30
- Oversight of Diagnostic Tests 32
- Designing Clinical Studies of Biomarkers 36
- Assessment and Adoption of Biomarker-Based Technologies 39
- Federal Programs for Technology Assessment 40
- Insurance Coverage Decisions and Practice Guidelines 43
- CMS Coverage of Biomarkers 46
- Economic Impact of Biomarkers 48
- Cost-Effectiveness Analysis 48
- The Value of Information and Research 53
- Technology Assessment in the Private Sector 53
- Clinical Development Strategies for Biomarker Utilization Discussion 57
- Strategies for Implementing Standardized Biorepositories Discussion 61
- Strategies for Determining Analytic Validity and Clinical Utility of Biomarkers Discussion 66
- Strategies to Develop Biomarkers for Early Detection Discussion 69
- Mechanisms for Developing an Evidence Base Discussion 73
- Evaluation of Evidence in Decision Making Discussion 76
- Incorporating Biomarker Evidence into Clinical Practice Discussion 80
- A Workshop Agenda 93
- B Workshop Speakers, Moderators, Invited Discussants, and Participants 99.
- Notes:
- Includes bibliographical references (page 92).
- ISBN:
- 0309101344
- 9780309101349
- OCLC:
- 70874173
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