Animal models in toxicology / edited by Shayne C. Gad.

Format:

Book

Contributor:

Gad, Shayne C., 1948-

Language:

English

Subjects (All):

Toxicology--Animal models.

Toxicity testing.

Animals, Laboratory.

Toxicology--methods.

Models, Animal.

Toxicity Tests.

Medical Subjects:

Animals, Laboratory.

Toxicology--methods.

Models, Animal.

Toxicity Tests.

Physical Description:

933 pages : illustrations ; 26 cm

Edition:

Second edition.

Place of Publication:

Boca Raton : CRC Taylor & Francis, 2007.

Summary:

Reflecting more than a decade's worth of changes, Animal Models in Toxicology, Second Edition is a practical guide to the common statistical problems encountered in toxicology and the methodologies that are available to solve them. The book presents a historical review of the use of animal models and an overview of broad considerations of metabolism and relevance used in toxicology. Individual chapters covering the eight major species used in toxicology and experimental biology form the core of the book. With contributions from experts in toxicology, toxicological pathology, and species-specific metabolism, each of these chapters provides an excellent introductory "course" along with guidance to the literature for more detailed understanding.

Features: Provides tables of normative physiology, pathology, reproductive, clinical laboratory, and metabolism data, Presents detailed discussions of husbandry, major diseases, and handling for the major species used in toxicology and experimental biology, Contains detailed descriptions and illustrations for dosing, blood collection, and other procedures, Reviews current laws and regulations governing animal care and use in major countries, Includes extensive appendices of acronyms, regulatory and scientific Web sites, animal suppliers, and a lexicon of terms used in describing clinical signs.

Contents:

The mouse

The rat

The hamster

The guinea pig

The rabbit

The ferret

The dog

Primates

The minipig

Alternative species / Shayne C. Gad

Clinical pathology of laboratory animals / Robert L. Hall

Model selection and scaling / Shayne C. Gad

Susceptibility factors / Shayne C. Gad

Laws and regulations governing animal care and use in research / Shayne C. Gad.

Notes:

Includes bibliographical references and index.

ISBN:

0824754077

9780824754075

OCLC:

62493286

Online:

Publisher description