The laboratory canine / Garrett Field, Todd A. Jackson.

Format:

Book

Author/Creator:

Field, Garrett.

Contributor:

Jackson, Todd A.

Series:

Laboratory animal pocket reference series

The laboratory animal pocket reference series

Language:

English

Subjects (All):

Dogs as laboratory animals.

Animals, Laboratory.

Dogs.

Medical Subjects:

Animals, Laboratory.

Dogs.

Genre:

Handbooks and manuals.

Physical Description:

159 pages : illustrations, forms ; 24 cm.

Place of Publication:

Boca Raton, FL : CRC Taylor & Francis, [2007]

Summary:

The Laboratory Canine clearly presents basic background information and common laboratory procedures covering subjects that apply specifically to dogs, such as basic biological features, husbandry, management, veterinary care, experimental methodology, and resources. The book offers guidance on performing a detailed physical examination, including necessary veterinary supplies, clinical signs of illness, clinical conditions, and reference tables of widely used veterinary drugs. It also examines anesthetic and surgical procedures that include pre-, intra-, and post-anesthesia/operative monitoring. It contains reference charts for monitoring patients through post-operative recovery and reference tables for anesthetics and analgesics. The book also discusses the human-animal bond, or the relationship between people and animals, and its significance and importance to the quality of research and the emotional health of staff caring for or working with animals.

Because dogs are a highly visible species in the eyes of the public and regulators, it is important that individuals working with laboratory canines have the proper training and experience. This valuable resource is ideal for those charged with the care and use of canines in a research setting. Features: Examines regulatory and accrediting agencies that may impact the use of dogs in research, Provides sources and suppliers of additional information on dogs, research, and veterinary supplies, Presents technical procedures in a clear format that can be easily incorporated into a facility's standard operating procedures, Describes a thorough and comprehensive cleaning and sanitation program.

Contents:

1 Important Biological Features 1

Origin of the Dog 1

Dog Breeds 3

Dog Behavior 4

Anatomic and Physiologic Features of Dogs 6

Normative Values of the Dog 8

2 Husbandry 17

Housing 17

Facility Design Considerations 17

Room Construction Features (Macroenvironment) 18

Outdoor Housing 20

Cage Materials and Design (Microenvironment) 20

Cage Size Standards 24

Environmental Conditions 25

Animal Care 26

Nutrition and Water 26

Environmental Enrichment 28

Exercise Requirements 31

Sanitation 32

Daily Schedule 34

Weekly Schedule 34

Semimonthly Schedule 34

Room Sanitation Schedule 35

Sanitation Quality Assurance Monitoring 35

Animal Receipt 36

Animal Identification 37

Transportation 39

Record Keeping 40

Husbandry Records 40

3 Management 45

Regulatory Agencies and Compliance 45

U.S. Department of Agriculture 45

Public Health Service, National Institutes of Health, and Office for Laboratory Animal Welfare 46

U.S. Food and Drug Administration and U.S. Environmental Protection Agency Good Laboratory Practice Regulations 47

The Association for Assessment and Accreditation of Laboratory Animal Care International 47

State and Local Agencies 48

Institutional Animal Care and Use Committee 48

Occupational Health and Safety 49

Zoonoses 50

Rabies 51

Scabies 51

Intestinal Helminthes 52

Giardiasis 52

Infections Resulting from Bite Wounds 52

Human-Animal Bond 53

4 Veterinary Care 57

Preventative Health Program 57

Quarantine, Stabilization, and Acclimation 58

Colony Separation 59

Clinical Management 59

Basic Veterinary Supplies 59

The Physical Examination 63

Clinical Signs of Illness in Dogs 69

Common Clinical Problems 70

Viral Diseases 70

Canine Parvovirus 70

Canine Distemper 71

Canine Coronavirus 72

Rabies 72

Kennel Cough 73

Bacterial Diseases 73

Leptospirosis 73

Parasitic Diseases 74

Protozoa 74

Nematodes 74

Cestodes 75

Arthropods 75

Fleas 75

Mites 76

Lice 76

Ticks 77

Fungal Diseases 77

Miscellaneous Diseases and Conditions 77

Interdigital Cysts 77

Juvenile Polyarteritis Syndrome: Beagle Pain Syndrome 78

Cherry Eye 78

Dental Conditions 79

Obesity 79

Implant Problems 79

Traumatic Injuries 80

Behavioral Disorders 80

Treatment of Diseases 80

General Treatment of Diarrhea 81

General Treatment of Dehydration 82

General Treatment of Anorexia 83

Drug Dosages in Dogs 83

Disease Prevention Through Sanitation 83

Anesthesia, Analgesia, and Sedation 84

Common Definitions 86

Principles of General Anesthesia 86

Stages of Anesthesia 89

Stage I Voluntary Excitement 89

Stage II Involuntary Excitement or Delirium 89

Stage III Surgical Anesthesia 89

Stage IV Medullary Paralysis and Respiratory Arrest 91

Assessment of the Depth of Anesthesia 91

Respiration 91

Cardiovascular 91

Reflexes 91

Ocular 92

Preanesthetic Management 92

Characteristics of Commonly Used Preanesthetics 93

Choosing an Anesthetic Regimen 93

Characteristics of Commonly Used Injectable Anesthetics 94

Principles of Gas Anesthesia 94

Characteristics of Commonly Used Gas Anesthetics 95

Principles of Local Anesthesia 95

Aseptic Surgery 96

Facilities, Features, and Equipment 96

Endotracheal Intubation 98

Personnel 101

Preoperative Preparation 101

Operating Room Procedures 102

Postsurgical Management 103

Guidelines for the Assessment of Signs of Pain in Animals 104

Blood Donors 104

Euthanasia 105

Signs of Morbidity (State of Disease or Illness) in Animals 105

Selected Criteria for Euthanasia of Moribund (State of Dying) Animals 106

5 Experimental Methodology 109

Canine Handling and Restraint 109

Mechanical Restraint Devices 111

Sample Collection Methods 112

Blood Collection 112

Urine Collection 116

Cerebrospinal Fluid Collection 119

Collection of Feces 120

Bone Marrow Collection 121

Test Article/Compound Administration Techniques 121

Formulation Guidelines 121

Volume Guidelines 122

Oral Dosing 123

Injection Sites 124

Implantable Osmotic Minipumps 124

Telemetry 125

Necropsy 128

Organizations 131

Publications 138

Periodicals 139

Electronic Resources 140

Canine Sources 141

Transportation Services/Resources 142

Laboratory Services 143

Feed 143

Equipment 144

Sanitation 144

Cages, Research, and Veterinary Supplies 145.

Notes:

Includes bibliographical references and index.

ISBN:

0849328934

9780849328930

OCLC:

69672029

Publisher Number:

9780849328930

Online:

Publisher description